二尖瓣脱垂与急性风湿性心脏炎的相关性研究
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作者：林红 陆堃 庞家传 阙绪光 吴妙玲 周令仪
单位：510080 广东省广州市，中山医科大学附属第一医院超声心动图室
关键词：风湿性心脏炎；二尖瓣脱垂；二尖瓣关闭不全
中国煤炭工业医学杂志000207 摘 要：目的探讨二尖瓣脱垂(MVP)与急性风湿性心脏炎(ARC)的相关性。方法对108例风湿热并ARC的患者行超声心动图检查以观察MVP的发生率。结果超声心动图检查发现MVP76例，发生率为70%，其中前叶脱垂57例(53%)，后叶脱垂13例(12%)，前后叶均脱垂6例(6%)。与对照组比较有明显的差异(P<0.01)。ARC所致MVP中74例(97%)并发二尖辫关闭不全(MI)，且MVP与MI的严重程度密切相关(P<0.01)。结论ARC是MVP，尤其是二尖瓣前叶脱垂的重要原因之一，而MVP是ARC所致MI的重要因素。
, 百拇医药 STUDY OF THE RELATIONSHIP BETEEN MITRAL VALVE PROLAPSE AND ACUTE RHEUMATIC CARDITIS
Lin Hong ,Lu Kun ,Pang Jiachuan
(the First Affiliated Hospital of Zhongshan Medical University, Guangzhou 510080)
Abstract：Objective To study the correlation features of mitral valve prolapse (MVP) with acute rheumatic carditis (ARC). Method 108 cases of rheumatic fever complicated with ARC received echocardiogram(ECG), and the incidence of MVP was observed. Result ECG indicated 76 cases of MVP with incidence of 70%, including 57 (53%) cases with anterior lobe prolapse, 13 (12%) cases with posterior lobe prolapse and 6 (6%) with both anterior and posterior lobe prolapse. This showed a remarkable difference (P<0.01) in contrast with the control group. Among the MVP patients caused by ARC, 74 patients (97%) were complicated with mitral insufficiency (MI), and MVP was closely correlated with the severity of MI (P<0.01). Conclusion ARC is one of the important factors causing MVP especially mitral anterior lobe prolapse, and MVP is the important factor that ARC leads to MI.
, 百拇医药
Keywords：rheumatic carditis mitral valve mitral insufficiency
参考文献：
[1]Tomaru T,Uchida Y,Mohri N,et al. Postinflammatory mitral and aortic valve prolapse:a clinical and pathological study. Circulation,1987,76(1):68～76.
[2]Marcus RH,Sareli P,Pocock WA,et al. Functional anatomy of severe mitral regurgitation in active rheumatic carditis. Am J Cardiol,1989,63(3):577～584.
, http://www.100md.com
[3]Zuppiroli A,Roman MJ,O'Grady M,et al. Lack of association between mitral valve prolapse and history of rheumatic fever. Am Heart J,1996,131(3):525～529.
[4]Darsee JR,Mikolich R,Nicoloff NB,et al. Prevalence of mitral valve prolapse in presumably healthy young men. Circulation, 1979,59(4):619～622.
[5]周令仪，胡瑞德.松弛瓣膜综合征—附 16例临床及病理分析.中华内科杂志，1986，25(3)：149～151.
[6]Lembo NJ,Dell'Italia LJ,Crawford MH,et al. Mitral valve prolapse in patients with prior rheumatic fever. Circulation,1988,7(4):830～836.
[7]Carpentier A, Chauvaud S, Fabiani JN, et al. Reconstructive surgery of mitral valve incompetence: ten-year appraisal. J Thorac Cardiovasc Surgery,1980,79(3):338～348.
收稿日期：1999-05-03
修稿日期：1999-07-21, 百拇医药
单位：510080 广东省广州市，中山医科大学附属第一医院超声心动图室
关键词：风湿性心脏炎；二尖瓣脱垂；二尖瓣关闭不全
中国煤炭工业医学杂志000207 摘 要：目的探讨二尖瓣脱垂(MVP)与急性风湿性心脏炎(ARC)的相关性。方法对108例风湿热并ARC的患者行超声心动图检查以观察MVP的发生率。结果超声心动图检查发现MVP76例，发生率为70%，其中前叶脱垂57例(53%)，后叶脱垂13例(12%)，前后叶均脱垂6例(6%)。与对照组比较有明显的差异(P<0.01)。ARC所致MVP中74例(97%)并发二尖辫关闭不全(MI)，且MVP与MI的严重程度密切相关(P<0.01)。结论ARC是MVP，尤其是二尖瓣前叶脱垂的重要原因之一，而MVP是ARC所致MI的重要因素。
, 百拇医药 STUDY OF THE RELATIONSHIP BETEEN MITRAL VALVE PROLAPSE AND ACUTE RHEUMATIC CARDITIS
Lin Hong ,Lu Kun ,Pang Jiachuan
(the First Affiliated Hospital of Zhongshan Medical University, Guangzhou 510080)
Abstract：Objective To study the correlation features of mitral valve prolapse (MVP) with acute rheumatic carditis (ARC). Method 108 cases of rheumatic fever complicated with ARC received echocardiogram(ECG), and the incidence of MVP was observed. Result ECG indicated 76 cases of MVP with incidence of 70%, including 57 (53%) cases with anterior lobe prolapse, 13 (12%) cases with posterior lobe prolapse and 6 (6%) with both anterior and posterior lobe prolapse. This showed a remarkable difference (P<0.01) in contrast with the control group. Among the MVP patients caused by ARC, 74 patients (97%) were complicated with mitral insufficiency (MI), and MVP was closely correlated with the severity of MI (P<0.01). Conclusion ARC is one of the important factors causing MVP especially mitral anterior lobe prolapse, and MVP is the important factor that ARC leads to MI.
, 百拇医药
Keywords：rheumatic carditis mitral valve mitral insufficiency
参考文献：
[1]Tomaru T,Uchida Y,Mohri N,et al. Postinflammatory mitral and aortic valve prolapse:a clinical and pathological study. Circulation,1987,76(1):68～76.
[2]Marcus RH,Sareli P,Pocock WA,et al. Functional anatomy of severe mitral regurgitation in active rheumatic carditis. Am J Cardiol,1989,63(3):577～584.
, http://www.100md.com
[3]Zuppiroli A,Roman MJ,O'Grady M,et al. Lack of association between mitral valve prolapse and history of rheumatic fever. Am Heart J,1996,131(3):525～529.
[4]Darsee JR,Mikolich R,Nicoloff NB,et al. Prevalence of mitral valve prolapse in presumably healthy young men. Circulation, 1979,59(4):619～622.
[5]周令仪，胡瑞德.松弛瓣膜综合征—附 16例临床及病理分析.中华内科杂志，1986，25(3)：149～151.
[6]Lembo NJ,Dell'Italia LJ,Crawford MH,et al. Mitral valve prolapse in patients with prior rheumatic fever. Circulation,1988,7(4):830～836.
[7]Carpentier A, Chauvaud S, Fabiani JN, et al. Reconstructive surgery of mitral valve incompetence: ten-year appraisal. J Thorac Cardiovasc Surgery,1980,79(3):338～348.
收稿日期：1999-05-03
修稿日期：1999-07-21, 百拇医药