电针足阳明经穴对家兔胃粘膜损伤防御性保护作用的研究

http://www.100md.com 2001年6月1日《中国针灸》 2001年第6期

     严洁常小荣刘建华邓常青李铁浪李江山易受乡林亚平

    (湖南中医学院针灸经络研究所,长沙410007)[摘要] 方法采用电针家兔足阳明经头面"四白"穴,躯干"梁门"穴、下肢"足三里"穴,观察其对胃粘膜损伤的防御性保护作用,以进一步探讨足阳明经与胃的相关性。结果电针足阳明经不同部位经穴,均可使家兔胃粘膜损伤指数显著降低,胃粘膜前列腺素E2(PGE2)及表皮生长因子(EGF)的含量增加,其中以"足三里"穴最为明显(P0.05)。结论电针足阳明经不同部位经穴,可能是通过胃粘膜组织中PGE2与EGF发挥了对胃粘膜细胞的保护作用, 证实了足阳明经与胃具有相关性。

    [主题词] 穴位,胃经;胃粘膜/针灸效应;前列腺素E/分析;内皮生长因子/分析

    Study on Protective Action of Electroacu puncture at Acupoints of the FootYangm i ng Channel on Lesion of Gastric Mucosa in Rabbits

    Yan Jie,Chang Xiaorong,Liu Jianhua,et al (Institute of AcupMoxibustion and Meridians,Hunan College of TCM,Changsha 410007)

    [Abstract] Purpose To probe into co rrelativity between the FootYangming Ch annel and stomach.Methods Protective actio n of electroacupuncture at"Sibai"(ST 2), " Liangmen"(ST 21)and"Zusanli"(ST 36)point s o f the FootYangming Channel on lesion of gastric mucosa was investigated in rabb its.Results Electroacupunctu re at the acupoint of different parts of the FootYangming Channel all can dec re ase significantly indexes of gastric muc osa lesion and contents of postaglandin E2 and endothelial growth factors(EGF) i n gastric macosa,with electroacupuncture of"Zusanli"(ST 36)having the most sigin i ficant increasing action(P0.05 ) .Conclusion Electroacupu ncture exerts possibly the protective ac tion on gastric mucosa cells through PGE 2 and EGF in gastric mucosa,which verif ies the correlativity between the FootYangming Channel and stomach. ......

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