芳基萘内酯型木脂素类化合物研究进展(7)
[62] Lee S S， Lin M T， Liu C L， et al. Six lignans from Phyllanthus myrtifolius[J]. J Nat Prod， 1996， 59(11)：1061.
[63] Souza da Silva S A， Souto A L， De Fatima Agra M， et al. A new arylnaphthalene type lignan from Cordia rufescens A. DC.(Boraginaceae)[J]. Arkivoc， 2004， 6：54.
[64] 陈耀祖，华苏明，陈能煜. 质谱学中的立体化学效应-鬼桕立体异构体的质谱研究[J]. 化学学报， 1985， 43(10)：960.
[65] Fonseca S F， Ruveda E A， McChesney J D. 13C NMR analysis of podophyllotoxin and some of its derivatives[J]. Phytochemistry， 1980， 19(7)：1527.
[66] 陆炜强，傅承新，赵云鹏.鬼臼毒素生物合成研究进展[J].中国中药杂志，2011，36(9)：1109.
[67] 崔亚君，刘晓峰，韩健，等.掌叶大黄悬浮培养细胞和根培养体系对鬼臼毒素的生物转化研究[J].中国中药杂志，2008，33(9)：989.
Advances in studies on aryltetralin lactone lignans
SUN Yan-jun1，2， WANG Jun-min1， CHEN Hong3， HUA Hui-ming2*
(1. School of Pharmacy， Henan University of Traditional Chinese Medicine， Zhengzhou 450046， China；
2. Key Laboratory of Structure-Based Drug Design & Discovery， Ministry of Education，Shenyang Pharmaceutical University， Shenyang 110016， China；
3. Pharmacognosy Division， Medical College of Chinese People′s Armed Police Force， Tianjin 300162， China)
[Abstract] Natural aryltetralin lactone lignans existed in the plants of family Berberidaceae， Acanthaceae， Burseraceae， Verbenaceae， Euphorbiaceae， etc. Due to the antineoplastic and antiviral properties， it has become a hot research topic in medicinal chemistry. This review covers extraction and isolation， biosynthesis， plant origin， and structure and spectral characteristics of natural aryltetralin lactone lignans. It will provide a useful reference for the intensive studies and rational utilization of aryltetralin lactone lignans.
[Key words] aryltetralin lactone； lignans； advances in studies
doi：10.4268/cjcmm20131303
[责任编辑 孔晶晶], 百拇医药(孙彦君，王俊敏，陈虹，华会明)
[63] Souza da Silva S A， Souto A L， De Fatima Agra M， et al. A new arylnaphthalene type lignan from Cordia rufescens A. DC.(Boraginaceae)[J]. Arkivoc， 2004， 6：54.
[64] 陈耀祖，华苏明，陈能煜. 质谱学中的立体化学效应-鬼桕立体异构体的质谱研究[J]. 化学学报， 1985， 43(10)：960.
[65] Fonseca S F， Ruveda E A， McChesney J D. 13C NMR analysis of podophyllotoxin and some of its derivatives[J]. Phytochemistry， 1980， 19(7)：1527.
[66] 陆炜强，傅承新，赵云鹏.鬼臼毒素生物合成研究进展[J].中国中药杂志，2011，36(9)：1109.
[67] 崔亚君，刘晓峰，韩健，等.掌叶大黄悬浮培养细胞和根培养体系对鬼臼毒素的生物转化研究[J].中国中药杂志，2008，33(9)：989.
Advances in studies on aryltetralin lactone lignans
SUN Yan-jun1，2， WANG Jun-min1， CHEN Hong3， HUA Hui-ming2*
(1. School of Pharmacy， Henan University of Traditional Chinese Medicine， Zhengzhou 450046， China；
2. Key Laboratory of Structure-Based Drug Design & Discovery， Ministry of Education，Shenyang Pharmaceutical University， Shenyang 110016， China；
3. Pharmacognosy Division， Medical College of Chinese People′s Armed Police Force， Tianjin 300162， China)
[Abstract] Natural aryltetralin lactone lignans existed in the plants of family Berberidaceae， Acanthaceae， Burseraceae， Verbenaceae， Euphorbiaceae， etc. Due to the antineoplastic and antiviral properties， it has become a hot research topic in medicinal chemistry. This review covers extraction and isolation， biosynthesis， plant origin， and structure and spectral characteristics of natural aryltetralin lactone lignans. It will provide a useful reference for the intensive studies and rational utilization of aryltetralin lactone lignans.
[Key words] aryltetralin lactone； lignans； advances in studies
doi：10.4268/cjcmm20131303
[责任编辑 孔晶晶], 百拇医药(孙彦君，王俊敏，陈虹，华会明)