大血藤中1个新的木脂素类化合物(8)
(1.Institute of China Materia Medica， China Academy of Chinese Medical Sciences， Beijing 100700， China；
2. National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines， Beijing 100700， China)
[Abstract] Sargentodoxae Caulis was prepared from the stems of Sargentodoxa cuneata.Twenty compounds from the the stems of S. cuneata collected in Huangshan Mountain， Anhui province， were isolated and purified by column chromatography on macroporous resin(HPD100)， silica gel， Sephadex LH-20 and semi-preparative HPLC.Their structures were elucidated on the basis of physicochemical properties and spectral data analyses as (7R，8S)-3，3′-5-trimethoxy-4，9-dihydroxy-4′，7-expoxy-5′，8-lignan-7′-en-9′-oic acid 4-O-β-D-glucopyranoside(1)， 1-O-(vanillic acid)-6-O-vanilloyl-β-D-glucopyranoside(2)， 4-hydroxyphenylethyl-6-O-coumaroyl-β-D-glucopyranoside(3)， citrusin B(4)， cinnamoside(5)，(-)-isolariciresinol 4′-O-β-D-glucopyranoside(6)，(-)-isolariciresinol 4-O-β-D-glucopyranoside(7)， 1-O-(vanillic acid)-6-(3″，5″-dimethoxy-galloyl)-β-D-glucopyranoside(8)， 4-hydroxyphenyl-ethyl-6-O-(E)-caffeoyl-β-D-glucopyranoside(9)， (-)-syringaresinol 4′-O-β-D-glucopyranoside(10)， (-)-syringaresinol di-O-β-D-glucopyranoside(11)， aegineoside(12)， calceolarioside B(13)， 4-hydroxy-3-methoxy-acetophenone-4-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside(14)， 4-hydroxy-3-methoxy-acetophenone-4-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside(15)，(-)-epicatechin(16)， salidroside(17)， 3，4-dihydroxy-phenyl ethyl-β-D-glucopyranoside(18)， chlorogenic acid(19) and protocatechuic acid(20). Compound 1 was a new compound and compounds 2-7 were isolated from this plant for the first time.
[Key words] Sargentodoxa cuneata； Lardizabalaceae； lignan； phenylethanoid glucoside
doi：10.4268/cjcmm20131317
[责任编辑 孔晶晶], http://www.100md.com(袁贤达，高慧敏，陈两绵，张启伟，王智民)
2. National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines， Beijing 100700， China)
[Abstract] Sargentodoxae Caulis was prepared from the stems of Sargentodoxa cuneata.Twenty compounds from the the stems of S. cuneata collected in Huangshan Mountain， Anhui province， were isolated and purified by column chromatography on macroporous resin(HPD100)， silica gel， Sephadex LH-20 and semi-preparative HPLC.Their structures were elucidated on the basis of physicochemical properties and spectral data analyses as (7R，8S)-3，3′-5-trimethoxy-4，9-dihydroxy-4′，7-expoxy-5′，8-lignan-7′-en-9′-oic acid 4-O-β-D-glucopyranoside(1)， 1-O-(vanillic acid)-6-O-vanilloyl-β-D-glucopyranoside(2)， 4-hydroxyphenylethyl-6-O-coumaroyl-β-D-glucopyranoside(3)， citrusin B(4)， cinnamoside(5)，(-)-isolariciresinol 4′-O-β-D-glucopyranoside(6)，(-)-isolariciresinol 4-O-β-D-glucopyranoside(7)， 1-O-(vanillic acid)-6-(3″，5″-dimethoxy-galloyl)-β-D-glucopyranoside(8)， 4-hydroxyphenyl-ethyl-6-O-(E)-caffeoyl-β-D-glucopyranoside(9)， (-)-syringaresinol 4′-O-β-D-glucopyranoside(10)， (-)-syringaresinol di-O-β-D-glucopyranoside(11)， aegineoside(12)， calceolarioside B(13)， 4-hydroxy-3-methoxy-acetophenone-4-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside(14)， 4-hydroxy-3-methoxy-acetophenone-4-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside(15)，(-)-epicatechin(16)， salidroside(17)， 3，4-dihydroxy-phenyl ethyl-β-D-glucopyranoside(18)， chlorogenic acid(19) and protocatechuic acid(20). Compound 1 was a new compound and compounds 2-7 were isolated from this plant for the first time.
[Key words] Sargentodoxa cuneata； Lardizabalaceae； lignan； phenylethanoid glucoside
doi：10.4268/cjcmm20131317
[责任编辑 孔晶晶], http://www.100md.com(袁贤达，高慧敏，陈两绵，张启伟，王智民)