中药治疗HAART相关血脂异常的临床研究(5)
7. Anhui Province Hospital of Traditional Chinese Medicine， Hefei 230031， China；
8. Beijing University of Chinese Medicine， Beijing 100018， China；
9. Beijing Chinese Medicine Hospital Affiliated to Capital Medical University， Beijing 100010， China)
[Abstract] Objective： To observe the effect and safety of Xiaozhi particles， integrated taohong Siwu tang and Erchen tang and Xuezhikang capsule in treating hyperlipidaemia (HLP) associated with highly active antiretroviral therapy (HAART). Method： In the multi-centered， randomized controlled clinical study，180 hyperlipidaemia associated with highly active antiretroviral therapy cases were divided into the treatment group treated by Xiaozhi particles， integrated Taohong Siwu tang and Erchen tang ，and the control group treated by Xuezhikang capsule.The treatment course was 12 weeks.The total cholesterol(Tch)， triglyceride(TG)， low density lipoprotein(LDL) and high-density lipoprotein(HDL) were observed. Result： After 12 weeks， compared with Xuezhikang capsule， the change difference of Tch， LDL， HDL in the Chinese traditional medicine formula groups of patients is significant (P<0.05)， the change of the TG has no significant difference. The effect of Tch， LDL in Xuezhikang capsule groups is better than in traditional Chinese medicine formula group，but the effect of HDL in traditional Chinese medicine formula group is better than in Xuezhikang capsule groups. Conclusion： Integrated Taohong Siwu tang and Erchen tang， Xiaozhi particles and Xuezhikang capsule can be used to control the hyperlipidaemia associated with highly active antiretroviral therapy as one of the main Chinese native medicine preparation.
[Key words] Xiaozhi particles integrated； Erchen tang； Taohong Siwu tang； Xuezhikang capsule； highly active antiretroviral therapy hyperlipidaemia
doi：10.4268/cjcmm20131505
[责任编辑 陈玲], 百拇医药(倪量 王融冰 郭会军 谭行华 孙丽君 郑煜煌 段呈玉 胡大庆 王文静 王玉光 赵)
8. Beijing University of Chinese Medicine， Beijing 100018， China；
9. Beijing Chinese Medicine Hospital Affiliated to Capital Medical University， Beijing 100010， China)
[Abstract] Objective： To observe the effect and safety of Xiaozhi particles， integrated taohong Siwu tang and Erchen tang and Xuezhikang capsule in treating hyperlipidaemia (HLP) associated with highly active antiretroviral therapy (HAART). Method： In the multi-centered， randomized controlled clinical study，180 hyperlipidaemia associated with highly active antiretroviral therapy cases were divided into the treatment group treated by Xiaozhi particles， integrated Taohong Siwu tang and Erchen tang ，and the control group treated by Xuezhikang capsule.The treatment course was 12 weeks.The total cholesterol(Tch)， triglyceride(TG)， low density lipoprotein(LDL) and high-density lipoprotein(HDL) were observed. Result： After 12 weeks， compared with Xuezhikang capsule， the change difference of Tch， LDL， HDL in the Chinese traditional medicine formula groups of patients is significant (P<0.05)， the change of the TG has no significant difference. The effect of Tch， LDL in Xuezhikang capsule groups is better than in traditional Chinese medicine formula group，but the effect of HDL in traditional Chinese medicine formula group is better than in Xuezhikang capsule groups. Conclusion： Integrated Taohong Siwu tang and Erchen tang， Xiaozhi particles and Xuezhikang capsule can be used to control the hyperlipidaemia associated with highly active antiretroviral therapy as one of the main Chinese native medicine preparation.
[Key words] Xiaozhi particles integrated； Erchen tang； Taohong Siwu tang； Xuezhikang capsule； highly active antiretroviral therapy hyperlipidaemia
doi：10.4268/cjcmm20131505
[责任编辑 陈玲], 百拇医药(倪量 王融冰 郭会军 谭行华 孙丽君 郑煜煌 段呈玉 胡大庆 王文静 王玉光 赵)