盛宏

    [摘 要]目的 探讨多西环素胶囊联合美诺平颗粒治疗痤疮的临床效果。方法 选择2021年1月-2022年6月泰州市疾病预防控制中心收治的86例痤疮患者为研究对象，随机分为对照组和试验组，各43例。对照组采用口服多西环素胶囊治疗，试验组在对照组基础上联合美诺平颗粒治疗，比较两组临床疗效、生活质量及不良反应发生情况。结果 试验组治疗总有效率为97.67%，高于对照组的72.09%，差异有统计学意义(P<0.05)；试验组治疗后角色功能、自我感知、社会功能、情感认知、睡眠质量、痤疮症状评分均高于对照组，差异有统计学意义(P<0.05)；试验组不良反应发生率为4.65%，低于对照组的20.93%，差异有统计学意义(P<0.05)。结论 多西环素胶囊联合美诺平颗粒治疗痤疮疗效确切，可提升患者生活质量，且不良反应发生几率较低，安全性较高。

    [关键词] 多西环素胶囊；美诺平颗粒；痤疮

    [中图分类号] R758.73+3 [文献标识码] A [文章编号] 1004-4949(2024)02-0032-04

    Clinical Effect of Doxycycline Capsules Combined with Menopine Granules in the Treatment of Acne

    SHENG Hong

    (Taizhou Center for Disease Control and Prevention， Taizhou 225300， Jiangsu， China)

    [Abstract]Objective To explore the therapeutic effect of doxycycline capsules combined with minophene granules in the treatment of acne. Methods A total of 86 acne patients admitted to Taizhou Center for Disease Control and Prevention from January 2021 to June 2022 were randomly divided into control group and experimental group， with 43 patients in each group. The control group was treated with oral doxycycline capsules ......