[摘 要] 带状疱疹后遗神经痛是带状疱疹后一种反复疼痛的后遗症，病程可持续多年。临床带状疱疹后遗神经痛患者主要特征是单侧神经性疼痛，会对患者的生活和心理造成严重影响。目前，关于带状疱疹后遗神经痛的发病机制尚未完全明确，可能与中枢神经、精神因素、周围神经发生病理性病变等因素相关。因此，临床无特效治疗方法，整体治疗效果相对较差。本文从带状疱疹后遗神经痛发病机制入手，并对治疗现状作一综述。

    [关键词] 带状疱疹后遗神经痛；发病机制；周围神经病变

    [中图分类号] R752.1 [文献标识码] A [文章编号] 1004-4949(2024)20-0187-04

    Research Progress on Pathogenesis and Treatment of Postherpetic Neuralgia

    ZHENG Qinghu， LAI Ping， LUN Xianpeng， WANG Weiyao， ZHANG Meihong， LI Bin， CHEN Zhenxiang

    (Department of Dermatology， No.988 Hospital of the PLA Joint Logistics Support Force， Zhengzhou 450042， Henan， China)

    [Abstract] Postherpetic neuralgia is a sequelae of recurrent pain after herpes zoster， and the course of disease can last for many years. The main feature of patients with clinical postherpetic neuralgia is unilateral neuropathic pain， which will have a serious impact on the patient’s life and psychology. At present， the pathogenesis of postherpetic neuralgia is not completely clear， which may be related to factors such as central nervous system， mental factors， and pathological lesions of peripheral nerves. Therefore ......