(广州市黄埔区中医医院内科广东广州 510700)【摘要】将临床Ⅱ型呼吸衰竭患者60例随即分为治疗组与对照组，治疗组采用可拉明联用纳洛酮静滴，对照组采用可拉明静滴。结果表明：治疗组临床症状及通气功能改善情况均优于对照组﹙P<0.01﹚；且治疗组副作用出现频率少于对照组。表明临床采用可拉明与纳洛酮联合应用优于单独应用可拉明。【关键词】可拉明； 纳洛酮； Ⅱ型呼吸衰竭； 对比观察【Abstract】Objective:To observe the influences of nikethamide combined with naloxone on the clinical therapeutic effect in treating Ⅱ type of respiratory failure. Methods:The cases of Ⅱ type of respiratory failure were randomly divided into treatment group (30 cases) and control group (30cases). The treatment group were treated with nikethamide and naloxone and the control group were only treatment with nikethamide through intravenous drip for 5 days. The clinical therapeutic effect and the change of PaCO2 and the Drug side effects were observed. Results: The total effective rate was 93.33% in treatment group and 80% in control group. The difference between the two groups was not significant (P=0.2542). But the treatment group come to effective quickly than the control group. And the PaCO2 reduced more than the control group. Conclusion: The treatment of nikethamide combined with naloxone is a kind of effective methods in treating Ⅱ type of respiratory failure, It can Alleviate the symptoms, reduced the PaCO2, and the Drug side effects was alleviate.【中图分类号】R563.8 【文献标识码】A【文章编号】1004-5511(2012)04-0193-01 Ⅱ型呼吸衰竭指低氧伴二氧化碳潴留 ......