心肌CaMKII与心脏功能衰退研究进展(2)
[2] Maier LS， Zhang T， Chen L， et al. Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling： reduced SR Ca2+ load and activated SR Ca2+ release. Circ Res. 2003 May 2；92(8)：904-11.
[3] Wang W， Zhu W， Wang S， et al. Sustained beta1-adrenergic stimulation modulates cardiac contractility by Ca2+/calmodulin kinase signaling pathway. Circ Res. 2004 Oct 15；95(8)：798-806.
[4] Ai X， Curran JW， Shannon TR， et al. Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure. Circ Res. 2005 Dec 9；97(12)：1314-22.
[5] Xu A， Narayanan N. Effects of aging on sarcoplasmic reticulum Ca2+-cycling proteins and their phosphorylation in rat myocardium. Am J Physiol. 1998 Dec；275(6 Pt 2)：H2087-94.
[6] Wang Y， Tandan S， Cheng J， Yang C， Nguyen L， Sugianto J， et al. Ca2+/calmodulin-dependent protein kinase II-dependent remodeling of Ca2+ current in pressure overload heart failure[J]. The Journal of biological chemistry. 2008，283(37)：25524-25532.
[7] Ling H， Zhang T， Pereira L， et al. Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest. 2009 May；119(5)：1230-40.
[8] Wagner S， Dybkova N， Rasenack EC， et al. Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. J Clin Invest. 2006 Dec；116(12)：3127-38.
[9] Sossalla S， Fluschnik N， Schotola H， et al. Inhibition of elevated Ca2+/calmodulin-dependent protein kinase II improves contractility in human failing myocardium. Circ Res. 2010 Oct 29；107(9)：1150-61.
[10] Zhang R， Khoo MS， Wu Y， Yang Y， Grueter CE， Ni G， et al. Calmodulin kinase II inhibition protects against structural heart disease[J]. Nature medicine. 2005，11(4)：409-417., http://www.100md.com(田旭)
[3] Wang W， Zhu W， Wang S， et al. Sustained beta1-adrenergic stimulation modulates cardiac contractility by Ca2+/calmodulin kinase signaling pathway. Circ Res. 2004 Oct 15；95(8)：798-806.
[4] Ai X， Curran JW， Shannon TR， et al. Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure. Circ Res. 2005 Dec 9；97(12)：1314-22.
[5] Xu A， Narayanan N. Effects of aging on sarcoplasmic reticulum Ca2+-cycling proteins and their phosphorylation in rat myocardium. Am J Physiol. 1998 Dec；275(6 Pt 2)：H2087-94.
[6] Wang Y， Tandan S， Cheng J， Yang C， Nguyen L， Sugianto J， et al. Ca2+/calmodulin-dependent protein kinase II-dependent remodeling of Ca2+ current in pressure overload heart failure[J]. The Journal of biological chemistry. 2008，283(37)：25524-25532.
[7] Ling H， Zhang T， Pereira L， et al. Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest. 2009 May；119(5)：1230-40.
[8] Wagner S， Dybkova N， Rasenack EC， et al. Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. J Clin Invest. 2006 Dec；116(12)：3127-38.
[9] Sossalla S， Fluschnik N， Schotola H， et al. Inhibition of elevated Ca2+/calmodulin-dependent protein kinase II improves contractility in human failing myocardium. Circ Res. 2010 Oct 29；107(9)：1150-61.
[10] Zhang R， Khoo MS， Wu Y， Yang Y， Grueter CE， Ni G， et al. Calmodulin kinase II inhibition protects against structural heart disease[J]. Nature medicine. 2005，11(4)：409-417., http://www.100md.com(田旭)