BiPAP通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床研究(1)
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2010年8月1日
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[摘要]目的探讨双水平无创正压通气(BiPAP)治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者的疗效。方法 87例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的患者随机分为时照组(43例)和试验组(44例)。在常规治疗的基础上,对照组给予低流量吸氧(2-5L/min),试验组接受BiPAP呼吸机治疗。在治疗前、治疗后24h及72h分别记录心率(HR)、呼吸频率(RR)及动脉血气指标(pH、PaCO2、PaO2)。结果 BiPAP通气治疗24h和72h后,试验组pH和PaO2较治疗前明显升高(P<0.05), HR、RR和PaCO2较治疗前显著下降(P<0.05),各项指标明显优于同期对照组(P< 0.05)。结论BiPAP无创通气可有效治疗肺慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭。
[关键词]双水平正压通气; 慢性阻塞性肺疾病; 呼吸衰竭
[中图分类号]R563.8[文献标识码]A [文章编号] 1005-0515(2010)-8-018-02
A clinical study of bi-leve positive airway pressure on patients with chronic obstructive pulmonary
disease complicated typeⅡ respiratory failure
MIAO Feng-binGUAN Yun-li
(Respiratory Department,the People,s Hospital of weiyuan county in Sichuan Province,642450,China)
[Abstract]ObjectiveTo explore the effect of bi-leve positive airway pressure(BiPAP) ventilation on the patients with chronic obstructive pulmonary diseas complicated typeⅡ respiratory failure. Methods Eighty-seven patients with chronic obstructive pulmonary diseas complicated typeⅡ respiratory failure were randomly divided into test group(44 cases)and control group(43 cases).Besides conventional treatments,the control group received routine oxygen therapy(2-5 L/min) and the test group received bi-level positive airway pressure(BiPAP)ventilation.The heart rate(HR),respiratory rate(RR), and arterial blood gas parameters(pH,PaCO2,PaO2)were recorded before and 24h, 72h after treatment. Results After 24h 、72h of BiPAP ventilation,the values of pH and PaO2 improved significantly and the values of HR ,RR and PaCO2 decreased obviously in the test group than those before treatment or those in the control group at same stage(P< 0.05,respectively). Conclusion BiPAP is a effective therapeutic method on patients with chronic obstructive pulmonary diseas complicated typeⅡ respiratory failure.
[Keywords]bi-level Positive airway pressure ventilation; Chronic obstructive pulmonary diseas; Respiratory failure
慢性阻塞性肺病(chronic obstructive pulmonary disease,COPD)是一组以气流受限为特征的肺部疾病,气流受限不完全可逆,呈进行性发展。是呼吸科的常见病、多发病,患病率和病死率均居高不下 ......
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