[摘要] 肝脏缺血再灌注是临床上常见的病理现象，近年的研究发现钙超载与氧化应激和多种炎症因子在再灌注损伤中起着重要作用，Kupffer细胞和一氧化氮分子同时具有保护和加重损伤双重作用。

    [关键词]肝脏;缺血再灌注损伤； 机理

    [中图分类号] R333.4[文献标识码] B[文章编号] 1005-0515(2011)-02-271-02

    [Abstract] The hepatic ischemia-reperfusion injury is one common clinical pathologic event.Recent studies have indicated that calcium-overloading, oxidative stress and various inflammative cytokines play very important roles in the ischemia-reperfusion injury, while Kupffer cells and nitric oxide exhibit double-edge effects with protection or exacerbation in the ischemia-reperfusion injury process.

    Keywords: Liver; Ischemia-reperfusion injury; Mechamism.

    肝脏缺血再灌注损伤(IRI)是临床上常见的病理现象 ......