磁共振弥散张量成像在常见脑肿瘤诊断中的临床应用研究(1)
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[摘要] 目的 研究和评价弥散张量成像在脑肿瘤中的临床应用价值。方法 胶质母细胞瘤8例、星形细胞瘤9例、脑膜瘤6例，共23例。行常规扫描及弥散张量成像(DTI)检查，测量兴趣区表观弥散系数(ADC)和各向异性指数(FA)，通过比较兴趣区ADC值和FA值，研究不同病变ADC值和FA值差异性存在的意义，并通过后处理技术直观表达出脑白质纤维束完整性和方向性与病变之间的关系。结果 (1)①胶质母细胞瘤感兴趣区ADC值/FA值为：肿瘤实体0.86±0.07/0.18±0.058， 肿瘤囊变坏死区2.79±0.16/0.05±0.018，瘤周水肿区1.86±0.071/0.12±0.049，临近正常白质区0.71±0.06/0.47±0.05。②星形细胞瘤(Ⅰ-Ⅱ级)感兴趣区ADC值/FA值为：肿瘤实体1.61±0.12/0.20±0.06，肿瘤囊变坏死区2.04±0.13/0.07±0.023，瘤周水肿区1.45±0.26/0.13±0.06，临近正常白质区0.71±0.07/0.47±0.06。③脑膜瘤感兴趣区ADC值/FA值为：肿瘤实体0.95±0.16/0.22±0.07，瘤周水肿区1.42±0.30/0.41±0.07，临近正常白质区0.71±0.06/0.47±0.08。(2)纤维束示踪成像三维显示病灶与相邻白质的关系，表现为神经束推移、分离和神经束破坏、浸润。结论 不同肿瘤之间及同类肿瘤的实体区、囊变坏死区、瘤周水肿区、正常脑白质ADC值和FA值存在明显差异、有重要的诊断价值；弥散张量成像技术(DTI)对临床手术方案的制定和病情预后判断有重要的指导意义。
[关键词] 磁共振成像； 弥散张量成像； 脑肿瘤； 神经纤维束成像
[中图分类号] R739.41 [文献标识码] B [文章编号] 1005-0515(2012)-02-020-02
Research on Magnetic Resonance Diffusion Tensor Imaging(MR-DTI) and its Clinical Applications in Diagnosis of Brain Tumors
Li Song Wa Weimin Yang Yun Luo Song Fang Zeyun Dai Dingwei
(The Department of Radiology of the People's Hospital in Dali, Yunnan, Dali, 671000)
[Abstract] Objective To research and evaluate the applications of clinical significance of MR-DTI in brain tumors. Methods 23 cases(including 8 cases with glioma,9 cases with astrocytoma,6 cases with meningioma) were underwent the conventional MRI and MR-DTI,FA and ADC values of regions of interest were measured. By making comparison of the ADC and FA values in tumor, zone of necrosis and cyst, peritumoral edema region and jacent white matter region, research the variability of ADC and FA values in different regions, and show the relationship directly between integrity, orientation of white matter fiber tract and tumors. Results (1)①ADC and FA values of ROI in glioma: tumor(0.86±0.07/0.18±0.058),zone of necrosis and cyst(2.79±0.16/0 ......
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