【摘要】 目的 比较阿立哌唑与利培酮治疗老年精神分裂症患者的临床疗效和安 全性。方法 对60例老年精神分裂症的住院患者随机分为两组，分别用阿立 哌唑和利培酮治疗8周。采用阳性与阴性症状量表(PANSS)评定疗效，用副反应量表(TESS)评 定不良反应。结果 阿立哌唑与利培酮治疗老年精神分裂症患者的临床疗效 差异无显著性。两组不良反应阿立哌唑组少而轻。结论 阿立哌唑治疗老年 精神分裂症疗效好，不良反应少。

    【关键词】 阿立哌唑；利培酮；老年精神分裂症

    Comparative Study of Aripiprazole and Risperidone in the Treatment of Senile Sch izophrenias. Zhu Jianzhong, Lu Zhixin, Lu Zhenglie. Wuxi Mental HealthCenter, Wuxi 214151, P.R.China

    【Abstract】 Objective To compare the eficacy and safety between aripi prazole and risperidone in the treatment of senile schizophrenia. Method s 60 senile sch izophrenias were randonfly divided into two groups. They received aripiprazole a nd fisperidone respectively for 8 weeks. The efficacies and side efects were ass essed by positive and negative symptom scale(PANSS), treatment emengent symptomscale(TESS). Results The efieacies of both aripiprazole and ris pefidone to trea t senile schizophrenias were similar, A had less effects than risperidone. Condusion Aripiprazole is all efective and safe drug in the treatmen t of senile schimphrenias. Its side efects were fewer. ......