清热利湿化瘀法对慢性盆腔炎患者细胞因子的影响(1)
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【中图分类号】R711.33【文献标识码】A【文章编号】1005-2720(2009)06-0148-02
【摘要】目的：观察清热利湿化瘀法治疗慢性盆腔炎的临床效果及其对细胞因子的影响。方法：将符合诊断标准的患者随机分为治疗组(30例)和对照组(30例)，分别采用清热利湿化瘀中药和单纯应用西药治疗，观察两组的近期临床疗效，细胞因子IL-1、IL-4等指标的变化情况。结果：治疗组和对照组的总有效率分别为86.67%和56.67%，两组相比差异有统计学意义(P<0.05)；两组治疗后均能降低IL-1，升高IL-4，但治疗组的上述作用显著优于对照组(P<0.05)。结论：清热利湿化瘀法治疗慢性盆腔炎的综合作用优于单纯使用抗生素，其治疗机制可能与抗炎和免疫调节有关。
【关键词】盆腔炎性疾病；祛瘀；清热；利湿；细胞因子
The influence of hotness-eliminating and dampness-eliminating and blood stasis-removing methods to cytokines of the patients with chronic pelvic inflammatory disease.Gong Lehui.(Department of Chinese medicine，the people’s hospital of Wulian county，Shandong 262300 China)
【Abstract】 Objective：To observe the clinical therapeutic effects of hotness-eliminating and dampness-eliminating and blood stasis-removing methods to cure the chronic pelvic inflammatory disease and its influences to the serum cytokines.Methods：The patients according with the diagnostic criteria were randomly divided into treatment group(30 cases)and control group(30 cases)，one was treated by the traditional Chinese medicine with effects of removing blood stasis and warming meridian and eliminating dampness，the other was treated only by western medicine，then we surveyed the clinical therapeutic effects and cytokines IL-1、IL-4 of each group were detected before an d after treatment.Results：The total effective rates of treat group and control group was respectively 86.67% and 56.67%，there were significant difference between two groups(P<0.05).There were similar effects that lowed the serum IL-1，raised IL-4，but the effects in treatment group were obviously superior to those of the control group(P<0.05).Conclusion：The synthetic effects of the hotness-eliminating and dampness-eliminating and blood stasis-removing methods is obviously superior to the antibiotic drug used only in treating chronic pelvic inflammatory，which may have a relation with the effects its anti-inflammatory and immunological regulation.
【Key Words】 Pelvic inflammatory disease；Blood act stasis remove；Removing dampness；Cytokines
慢性盆腔炎是妇科常见病、多发病，病程长，反复发作，可导致不孕不育、宫外孕等严重后果。其病程长，临床表现复杂，临床治疗效果差。根据其不同的临床表现、不同阶段及病变部位，分属中医“少腹痛”、“带下病”、“月经不调”等范畴。笔者采用清热利湿化瘀法治疗本病30例，并设西药治疗对照组30例，取得满意的临床效果，现报告如下： ......
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