通讯作者：张国民，E-mail：834095773@qq.com

    increased (P<0.01)；levels of FSH and LH， and expressions of Fas and Fas-L mRNA significantly decreased (P<0.05). Conclusion Bushen Huoxue Prescription can decrease expressions of Fas and Fas-L mRNA to inhibit cell apoptosis by adjusting the hormone level of hypothalamus-pituitary- ovarianaxis.

    Key words：Bushen Huoxue Prescription；premature ovarian failure；granulose cell；cell apoptosis；mice

    卵巢早衰(Premature ovarian failure ......