异常黏液质成熟剂对APP/PS1转基因阿尔茨海默病小鼠学习记忆和脑组织RAGE、LRP1蛋白表达的影响(2)
基金项目:教育部新世纪优秀人才计划(NCET-11-1073)通讯作者:努尔买买提·艾买提,E-mail:Oglan1972@126.com
Compared with the model control group, the LRP1 expression decreased and RAGE increased in Abnormal Phlegmatic Munziq high-, medium-, and low-dose groups (P<0.05,P<0.01). Conclusion Abnormal Phlegmatic Munziq can improve ability of spatial learning and memory in APP/PS1 mice and regulate the expressions of RAGE and LRP1.
Key words: Abnormal Phlegmatic Munziq; APP/PS1 transgenic mice; spatial learning and memory; hippocampal CA1; RAGE; LRP1
阿尔茨海默病(Alzheimer's disease ......
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