活血除痹汤对硬皮病小鼠皮肤血小板衍生生长因子A和转移生长因子—β表达的影响(2)
基金项目：北京中医药大学自主选题项目(2013-JYBZZ-XS-189)通讯作者：段行武，E-mail：xwduan@sina.com
group significantly increased than blank group (P<0.01)； the expression of the mentioned indicators were statistically significant lower in the TCM high-， medium-， low-dose group than model group； The expressions of PDGF-A and TGF-β showed a positive correlation with the amount of COL-Ⅰ and COL-Ⅲpresented in each group. Conclusion Huoxue Chubi Decoction can suppress collagen expression and fibroblast formation in skin lesion of scleroderma mice models by down regulating the expressions of TGF-β and PDGF-A ......
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