关键词:网络药理学;靶点预测;作用机制;复方配伍;综述
中图分类号:R285;R2-05 文献标识码:A 文章编号:1005-5304(2020)03-0133-04
DOI:10.3969/j.issn.1005-5304.201904311
Application of Network Pharmacology in Research on Mechanism of Action of TCM Compounds
ZHAO Bingcong1, LI Yahong1, XIE Hongxia2
1. College of Graduate, Inner Mongolia Medical University, Hohhot 010110, China; 2. Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010059, China
Abstract: Network pharmacology which depends on a network-construction idea of “multi components, multi targets and multi pathways” is consistent with the “integrality” concept which plays an important role in TCM theory. It is more convenient and precise to predict and analyze the mechanism of action of TCM compounds, and can expound and demonstrate some viewpoints commonly used in the compatibility of TCM. Therefore, network pharmacology has received extensive attention and recognition from scholars in recent years. This article reviewed the literature on the mechanism of action of TCM compounds in the past 5 years, and discussed the compatibility laws and regulations of “emperor, minister, adjuvant and courier” medicine (which were called jun-chen-zuo-shi in Chinese), medicinal pairs, different treatments for the same disease, and same treatment for different disease from the research process of network pharmacology., 百拇医药(赵炳聪 李亚鸿 解红霞)