噻唑烷二酮类药物抑制肿瘤细胞作用研究进展(4)
[13] Ohta T， Elnemr A， Yamamoto M， et al. Thiazolidinedione， a peroxisome proliferator-activated receptor-γ ligand， modulates the E-cadherin/h-catenin system in a human pancreatic cancer cell line， BxPC-3[J]. Int J Oncol， 2002， 21(1)： 37-42.
[14] Chang TH， Szabo E. Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor γ in non-small cell lung cancer[J]. Cancer Res， 2000， 60(4)： 1129-1138.
[15] Huang JW， Shiau CW， Yang YT， et al. Peroxisome proliferator-activated receptor γ-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells[J]. Mol Pharmacol， 2005， 67(4)： 1342-1348.
[16] Chen F， Harrison LE. Ciglitazone-induced cellular anti-proliferation increases p27kip1 protein levels through both increased transcriptional activity and inhibition of proteasome degradation[J]. Cell Signal， 2005， 17(7)： 809-816.
[17] Chen F， Kim E， Wang CC， et al. Ciglitazone-induced p27 gene transcriptional activity is mediated through Sp1 and is negatively regulated by the MAPK signaling pathway[J]. Cell Signal， 2005， 17(12)： 1572-1577.
[18] Kim Y， Suh N， Sporn M， et al. An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis[J]. J Biol Chem， 2002， 277(25)： 22320-22329.
(收稿日期：2012-09-05)
, 百拇医药(尤文 张杰)
[14] Chang TH， Szabo E. Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor γ in non-small cell lung cancer[J]. Cancer Res， 2000， 60(4)： 1129-1138.
[15] Huang JW， Shiau CW， Yang YT， et al. Peroxisome proliferator-activated receptor γ-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells[J]. Mol Pharmacol， 2005， 67(4)： 1342-1348.
[16] Chen F， Harrison LE. Ciglitazone-induced cellular anti-proliferation increases p27kip1 protein levels through both increased transcriptional activity and inhibition of proteasome degradation[J]. Cell Signal， 2005， 17(7)： 809-816.
[17] Chen F， Kim E， Wang CC， et al. Ciglitazone-induced p27 gene transcriptional activity is mediated through Sp1 and is negatively regulated by the MAPK signaling pathway[J]. Cell Signal， 2005， 17(12)： 1572-1577.
[18] Kim Y， Suh N， Sporn M， et al. An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis[J]. J Biol Chem， 2002， 277(25)： 22320-22329.
(收稿日期：2012-09-05)
, 百拇医药(尤文 张杰)