社区慢性肾病高危人群中药饮片干预效果评价(1)
摘 要 目的：评价在治疗原发疾病基础上，对慢性肾病高危人群采用中药饮片强化干预的效果。方法：按闸北区社区慢性肾病高危人群基线调查结果，纳入慢性肾病高危人群197例，采用随机配对法将患者分为干预组92例，对照组105例。干预组接受中药饮片，对照组采用常规原发疾病防治，共干预6个月。观察干预组服药依从率，两组尿微量白蛋白控制有效率、慢性肾病危险因素(血压、空腹血糖)的变化及改善情况。结果：干预组接受中药饮片干预依从率为76.63%，尿微量白蛋白总体控制有效率为84.78%，尿微量白蛋白低于对照组，两组之间差别具有统计学意义(t=2.0503，P<0.05)，重复测量方差分析显示干预组、对照组组间尿微量白蛋白(t=16.613，P<0.05)，表明随干预时间的延长，干预组累积效应更明显；慢性肾病危险因素：干预6个月后，干预组研究对象收缩压降至128.62±7.18 mmHg，舒张压降至78.31±5.01 mmHg，空腹血糖降至6.01±1.53 mmol/L，而对照组较前上升。结论：在控制原发疾病的基础上辅以强化的中药饮片干预对控制社区慢性肾病高危人群发展成为慢性肾病患者和延缓疾病发展进程具有一定的社会意义，对将减轻患者及其家庭经济负担，减少社会疾病经济负担具有重要作用。
关键词 慢性肾病 高危人群 中药饮片干预
中图分类号：R692 文献标识码：A 文章编号：1006-1533(2015)16-0034-04
Evaluation of the effect of the Chinese herbal decoction pieces in the intervention on the high risk population with the community chronic kidney disease
WANG Junqi1， TAO Haiqi1， ZHAO Xinping2， TAO Minglong3， SANG Jiuhua1(1.Pengpu Community Health Service Center of Zhabei District， Shanghai 200072， China； 2. Public Health College of Fudan University，Shanghai 200032， China； 3. Yueyang Traditional Chinese and Western Medicine Hospital， Shanghai 200437， China)
ABSTRACT Objective： To evaluate the effect of the strengthened intervention of Chinese herbal decoction pieces on the high risk population with the chronic kidney disease (CKD) based on the treatment of the primary disease. Methods： According to the baseline survey of the high risk population with the community CKD in Zhabei District， 197 high risk cases with CKD were selected and divided into an intervention group with 92 cases and a control group with 105 ones randomly. The intervention group received the intervention of Chinese herbal decoction pieces and the control group with the routine prevention and treatment for the primary disease， both of whom were intervened for 6 months. The compliance rate of the intervention group and the effective control rate of urinary albumin and the change and improvement of CKD risk factors ( blood pressure， and fasting blood glucose) in both groups were observed. Results： In the intervention group， the compliance rate of accepting the Chinese herbal decoction pieces was 76.63%， the overall effective rate of urinary albumin 84.78% and lower than in the control group， and there was a significant difference between two groups (t=2.0503， P<0.05). The repeated measures ANOVA showed that the urinary albumin between the intervention and control groups was (t=16.613， P<0.05)， which indicated that with the intervention time， the cumulative effect in the intervention group was more obvious. In the CKD risk factors， after 6 months intervention， the systolic blood pressure dropped to 128.62± 7.18 mmHg， and the diastolic blood pressure to 78.31±5.01 mmHg， and the fasting plasma glucose to 6.01±1.53 mmol/ L in the intervention group， while the three indexes in the control group rose compared with the previous. Conclusion： Based on the control of the primary disease， it has the social significance in strengthening the intervention of Chinese herbal decoction pieces to control CKD high risk population to develop into the CKD patients and delay the progression of the disease process and can undertake the important role of reducing the economic burdens of the patients and their families and the social disease., http://www.100md.com(王俊琪 陶海琦 赵新平 陶明龙 桑久华)
关键词 慢性肾病 高危人群 中药饮片干预
中图分类号：R692 文献标识码：A 文章编号：1006-1533(2015)16-0034-04
Evaluation of the effect of the Chinese herbal decoction pieces in the intervention on the high risk population with the community chronic kidney disease
WANG Junqi1， TAO Haiqi1， ZHAO Xinping2， TAO Minglong3， SANG Jiuhua1(1.Pengpu Community Health Service Center of Zhabei District， Shanghai 200072， China； 2. Public Health College of Fudan University，Shanghai 200032， China； 3. Yueyang Traditional Chinese and Western Medicine Hospital， Shanghai 200437， China)
ABSTRACT Objective： To evaluate the effect of the strengthened intervention of Chinese herbal decoction pieces on the high risk population with the chronic kidney disease (CKD) based on the treatment of the primary disease. Methods： According to the baseline survey of the high risk population with the community CKD in Zhabei District， 197 high risk cases with CKD were selected and divided into an intervention group with 92 cases and a control group with 105 ones randomly. The intervention group received the intervention of Chinese herbal decoction pieces and the control group with the routine prevention and treatment for the primary disease， both of whom were intervened for 6 months. The compliance rate of the intervention group and the effective control rate of urinary albumin and the change and improvement of CKD risk factors ( blood pressure， and fasting blood glucose) in both groups were observed. Results： In the intervention group， the compliance rate of accepting the Chinese herbal decoction pieces was 76.63%， the overall effective rate of urinary albumin 84.78% and lower than in the control group， and there was a significant difference between two groups (t=2.0503， P<0.05). The repeated measures ANOVA showed that the urinary albumin between the intervention and control groups was (t=16.613， P<0.05)， which indicated that with the intervention time， the cumulative effect in the intervention group was more obvious. In the CKD risk factors， after 6 months intervention， the systolic blood pressure dropped to 128.62± 7.18 mmHg， and the diastolic blood pressure to 78.31±5.01 mmHg， and the fasting plasma glucose to 6.01±1.53 mmol/ L in the intervention group， while the three indexes in the control group rose compared with the previous. Conclusion： Based on the control of the primary disease， it has the social significance in strengthening the intervention of Chinese herbal decoction pieces to control CKD high risk population to develop into the CKD patients and delay the progression of the disease process and can undertake the important role of reducing the economic burdens of the patients and their families and the social disease., http://www.100md.com(王俊琪 陶海琦 赵新平 陶明龙 桑久华)