摘 要 脑小血管病是一组与年龄相关的、涉及多种病因导致的多种病理学过程的疾病，已知与认知功能障碍关系密切，但影响认知功能的具体机制及结果尚未完全明确。本文介绍脑小血管病的概念、分类及其与认知功能障碍的关系，以期为进一步研究捋清思路。

    关键词 脑小血管病 认知功能障碍 痴呆症

    中图分类号：R749.13； R743.9 文献标志码：A 文章编号：1006-1533(2018)17-0009-04

    Cerebral small vessel disease and cognitive impairment*

    ZHANG Shufan， LUO Yufan， WU Danhong**

    (Department of Neurology， Shanghai 5th People’s Hospital， Fudan University， Shanghai 200240， China)

    ABSTRACT Cerebral small vessel disease (CSVD) is a group of age-related disease that involves in multiple pathological processes caused by multiple pathologies. It is known that it has a close relationship with cognitive function. At present ......