【摘要】目的:探讨本院抗菌药品不良反应的发生情况,分析引发不良反应的相关因素,指导临床安全用药。方法:收集本院83例抗菌药品不良反应资料,按照患者的性别、年龄、药品种类、给药途径和不良反应表现进行统计和分析。结果:83例报告中女性多于男性,静脉滴注引发的最多,皮肤及其附件反应最多见,其中喹诺酮类31例(37.35%),是不良反应最多的一类。结论:随着抗菌类药品种类和使用不断增加,不良反应也日益增多,发生因素与患者年龄、性别、药品种类等有关,所以临床医生要合理使用抗菌类药物,减少不良反应的发生。

    【关键词】药品不良反应;抗菌类药品;统计分析

    Analysis on 83 cases of adverse drug reactions by anti-infective drugs

    ZHONG Li

    【Abstract】Objective: To observe the occurrence of adverse drug reactions caused by anti-infective drugs in our hospital and analyze its correlative factors for their safe use in clinical practice.Methods:83 cases of adverse drug reactions were collected in our hospital and were analyzed statistically according to the patients' sexes, ages, drug varieties, administering methods and clinical presentations. Results: Of the 83 patients, females were more than males, the first of all the drugs involved in the present study, the most frequent in skin and its appendages and commonly quinolones 36 cases(43.37%). Conclusion: The adverse drug reactions frequency was increased with involement of many kinds of anti-infective drugs, mostly by injection,the occurrence of ADR is related to many factors, such as age of patients,the patients'sexes and category of drug. Rational use of anti-infective drugs should be taken to decrease the occurrence of adverse reactions. ......