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稳心颗粒与普罗帕酮治疗室性期前收缩疗效的对比研究
http://www.100md.com 2009年8月1日 《医学信息·下旬刊》 2009年第8期
稳心颗粒与普罗帕酮治疗室性期前收缩疗效的对比研究
稳心颗粒与普罗帕酮治疗室性期前收缩疗效的对比研究

     【摘要】目的:对比观察稳心颗粒与普罗帕酮对室性期前收缩的疗效及安全性。方法:随机选取有明显临床症状的室性期前收缩者205例,随机分为2组,稳心颗粒组(n=104例)口服稳心颗粒1包(9g)tid;普罗帕酮组(n=101例)口服普罗帕酮150mg tid均治疗4周为1疗程,观察用药前后临床症状,期前收缩次数及不良反应情况。结果:稳心颗粒治疗组总有效率81.7%。普罗帕酮治疗组总有效率为84.2%,两组比较差异无统计学意义(P>0.05),试验组的不良反应发生率为4.81%,对照组为8.91%,差异有显著性(P<0.05)。结论:稳心颗粒对室性期前收缩有效率与普罗帕酮相似,且该药安全,无明显不良反应。

    【关键词】稳心颗粒;普罗帕酮;室性期前收缩

    Effecs of wenxin graule and propafenone on premature wen tricucar beats

    MA Xifan

    【Abstrace】Objective:TO observe the effect and Safety of wenxin granule and propafenone on premature ventricular beats Methad;It were selected 205.premature ventricular beats patienes with obviously clinical symptom,who were randomly divided into two groups:wenxin group(n=104)taken wensin granule tid ,the control group(n=101)taken propafenone 150mg tid for 4 weeks .Then observed the offect of premature .venericucar beats.symptoms and adverse effdcts. Results The efficiency was 81.7%in wenxin group and it was 84.2% in propafenone group .The antiarrhythmia effect of wenxin for premature ventricular beats as same as that of propafenone (P>0.05),adverse effects were significantly less.than that of propafenone (P<0.05).Conclusion:The efficieney of wenxin granule is as well as propafenone on premafure ventricular beats . but wenxin granule is better in improver ovemente of adverse effects and safer than propafenone. ......

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