儿泻停颗粒联合凝结芽孢杆菌活菌片治疗小儿迁延性腹泻疗效观察(1)
摘要：目的 探讨儿泻停颗粒联合凝结芽孢杆菌活菌片治疗小儿迁延性腹泻的疗效观察。方法 选取迁延性腹泻患儿60例，随机分为观察组和对照组。两组患儿均予以指导喂养、调整饮食、预防或纠正脱水和酸中毒等基础治疗。观察组在此基础上予以儿泻停颗粒联合凝结芽孢杆菌活菌片治疗，对照组在此基础上予以蒙脱石散联合凝结芽孢杆菌活菌片治疗。观察两组患儿治疗后食欲、精神恢复情况，并比较其治疗(7±1)d的临床有效率。结果 观察组患儿的食欲增强、食量增加、神疲倦怠改善等恢复时间短于对照组(均P<0.05)。治疗7 d后，观察组患儿的临床总有效率(93.0%)明显高于对照组(80.0%)(P<0.05)。结论 儿泻停颗粒联合凝结芽孢杆菌活菌片治疗儿童迁延性腹泻的疗效确切，能明显改善患儿的临床症状及体征，缩短治疗的病程。
关键词：迁延性腹泻；儿童；儿泻停；凝结芽孢杆菌
To Observe the Curative Effect of Erxieting Granule Combined with Bacillus Coagulans Tablets in the Treatment of Infantile Persistent Diarrhea
, 百拇医药
SHI Wei-xin
(Department of Gastroenterology，Changzhou Children's Hospital，Changzhou 213003，Jiangsu，China)
Abstract：Objective To investigate the Erxieting Granule combined Bacillus Coagulans Tablets curative effect observation of treatment of diarrhea of children. Methods Selection of diarrhea of children with 60 cases， were randomly divided into observation group and control group. Both groups of children with guidance of feeding， adjust the diet， and prevent or correct dehydration and acidosis foundation treatment. Observation group based on this to Erxieting Granule combined Bacillus Coagulans Tablets treatment， the control group on the basis of this to montmorillonite powder combined Bacillus Coagulans Tablets treatment. Observed two groups of children with appetite， mental recovery after treatment， and compare the clinical effectiveness for the treatment of 7 ± 1d. Results Observation group with increased appetite， eat more， god tired idle to improve recovery time shorter than the control group (all P< 0.05). 7 d after treatment， the observation group with the clinical total effective rate (93.0%) is significantly higher than control group (80.0%) (P< 0.05). Conclusion Erxieting Granule combined Bacillus Coagulans Tablets treatment of diarrhea of children curative effect， can significantly improve the patient's clinical symptoms and signs， shorten the course of treatment.
, 百拇医药
Key words：Protracted diarrhea； Children； Eexieting； Condensation bacillus
腹瀉病是一组多病原多因素引起的疾病，发病率较高，尤其多见于6～12个月的小儿，由于儿童营养状况及医疗条件的改善，在我国本病的病死率已明显下降，但由于各种原因，仍然有将近3%～20%的腹泻病发展成迁延性腹泻。儿童迁延性腹泻多由于急性腹泻病、营养不良、免疫功能低下、肠道反复感染引起[1]。临床上多予以抗生素药物治疗，但是实践已证明，不合理滥用抗生素会导致条件致病菌易位，引起肠道菌群失衡，造成肠道功能紊乱，营养吸收不良，继发双重感染，最后形成恶性循环[2]，进一步导致生长发育减缓甚至倒退，严重威胁婴幼儿生长发育及健康，治疗上困难度较大。
中成药儿泻停用于治疗小儿急性腹泻的临床报道较多，我院小儿消化科尝试使用儿泻停颗粒联合凝结芽孢杆菌活菌片治疗迁延性腹泻。本次疗效观察选取60例迁延性腹泻病患儿作为研究对象，着重观察对比了儿泻停颗粒联合凝结芽孢杆菌活菌片治疗小儿迁延性腹泻病患儿的临床疗效，现具体分析如下。
1 资料与方法
1.1一般资料及分组 收集并选取2015年4月1日～7月31日常州市儿童医院消化内科门诊和住院部收治的迁延性腹泻病患儿作为研究对象，以《中国腹泻病诊断治疗方案》为标准[3]，患儿均经抗生素与中药内服治疗且效果不佳，病程为2w～2个月，有反复腹泻、食欲减退等消化道功能障碍症状，且经大便常规检查和大便培养结果排除细菌性痢疾、霉菌感染等。, http://www.100md.com(史伟新)
关键词：迁延性腹泻；儿童；儿泻停；凝结芽孢杆菌
To Observe the Curative Effect of Erxieting Granule Combined with Bacillus Coagulans Tablets in the Treatment of Infantile Persistent Diarrhea
, 百拇医药
SHI Wei-xin
(Department of Gastroenterology，Changzhou Children's Hospital，Changzhou 213003，Jiangsu，China)
Abstract：Objective To investigate the Erxieting Granule combined Bacillus Coagulans Tablets curative effect observation of treatment of diarrhea of children. Methods Selection of diarrhea of children with 60 cases， were randomly divided into observation group and control group. Both groups of children with guidance of feeding， adjust the diet， and prevent or correct dehydration and acidosis foundation treatment. Observation group based on this to Erxieting Granule combined Bacillus Coagulans Tablets treatment， the control group on the basis of this to montmorillonite powder combined Bacillus Coagulans Tablets treatment. Observed two groups of children with appetite， mental recovery after treatment， and compare the clinical effectiveness for the treatment of 7 ± 1d. Results Observation group with increased appetite， eat more， god tired idle to improve recovery time shorter than the control group (all P< 0.05). 7 d after treatment， the observation group with the clinical total effective rate (93.0%) is significantly higher than control group (80.0%) (P< 0.05). Conclusion Erxieting Granule combined Bacillus Coagulans Tablets treatment of diarrhea of children curative effect， can significantly improve the patient's clinical symptoms and signs， shorten the course of treatment.
, 百拇医药
Key words：Protracted diarrhea； Children； Eexieting； Condensation bacillus
腹瀉病是一组多病原多因素引起的疾病，发病率较高，尤其多见于6～12个月的小儿，由于儿童营养状况及医疗条件的改善，在我国本病的病死率已明显下降，但由于各种原因，仍然有将近3%～20%的腹泻病发展成迁延性腹泻。儿童迁延性腹泻多由于急性腹泻病、营养不良、免疫功能低下、肠道反复感染引起[1]。临床上多予以抗生素药物治疗，但是实践已证明，不合理滥用抗生素会导致条件致病菌易位，引起肠道菌群失衡，造成肠道功能紊乱，营养吸收不良，继发双重感染，最后形成恶性循环[2]，进一步导致生长发育减缓甚至倒退，严重威胁婴幼儿生长发育及健康，治疗上困难度较大。
中成药儿泻停用于治疗小儿急性腹泻的临床报道较多，我院小儿消化科尝试使用儿泻停颗粒联合凝结芽孢杆菌活菌片治疗迁延性腹泻。本次疗效观察选取60例迁延性腹泻病患儿作为研究对象，着重观察对比了儿泻停颗粒联合凝结芽孢杆菌活菌片治疗小儿迁延性腹泻病患儿的临床疗效，现具体分析如下。
1 资料与方法
1.1一般资料及分组 收集并选取2015年4月1日～7月31日常州市儿童医院消化内科门诊和住院部收治的迁延性腹泻病患儿作为研究对象，以《中国腹泻病诊断治疗方案》为标准[3]，患儿均经抗生素与中药内服治疗且效果不佳，病程为2w～2个月，有反复腹泻、食欲减退等消化道功能障碍症状，且经大便常规检查和大便培养结果排除细菌性痢疾、霉菌感染等。, http://www.100md.com(史伟新)
参见：首页 > 医疗版 > 症状 > F > 腹泻