相对低分子质量肝素钠联合奥扎格雷钠治疗脑血栓形成的疗效评析(1)
摘要：目的 评析相对低分子质量肝素鈉联合奥扎格雷钠治疗脑血栓形成的疗效。方法 将2015年4月～2016年9月作为研究时段，选择此时间段内的92例脑血栓的患者作为研究对象，随机将其分为对照组和观察组各46例，对照组采用常规的治疗方法，观察组采用相对低分子质量肝素钠联合奥扎格雷钠进行治疗，对比和分析两组患者的治疗效果和各项实验室检查结果。结果 观察组总有效率为93.47%、对照组总有效率为78.26%，组间存在较大差异(P<0.05)，具有统计学意义。观察组全血粘度、血浆粘度、血小板黏附率、总胆固醇以及血细胞比容等指标明显优于对照组(P<0.05)，组间差异具有统计学意义。结论 对于脑血栓形成的患者采取相对低分子质量肝素钠联合奥扎格雷钠的治疗方法能够有效的改善患者各项实验室指标，从而提高治疗效果，利于患者疾病的康复，具有临床推广价值。
关键词：相对低分子质量肝素钠；奥扎格雷钠；脑血栓
中图分类号：R743.3 文献标识码：A 文章编号：1006-1959(2017)16-0083-02
, 百拇医药
Evaluation of Curative Effect of Relatively Low Molecular Weight Heparin Sodium Combined with Ozagrel in the Treatment of Cerebral Thrombosis
MENG Xian-pu
(2 Cases of Xinbin Manchu Autonomous County People's Hospital，Fushun 113200，Liaoning，China)
Abstract：Objective To evaluate on curative effect of low molecular weight heparin combined with sodium ozagrel in the treatment of cerebral thrombosis.Methods In April 2015～September 2016，as the research period，92 patients with cerebral thrombosis in this period were selected as the research object.They were randomly divided into the control group and the observation group，each with 46 cases，the control group was treated with conventional methods，the observation group with low molecular weight heparin combined with sodium ozagrel in treatment，comparison and analysis of two groups of patients and the results of laboratory examination.Results The total effective rate of observation group was 93.47%，control group total effective rate was 78.26%，there was a significant difference between the two groups(P<0.05)，which was statistically significant.The observation group of whole blood viscosity，plasma viscosity，platelet adhesion rate，total cholesterol and hematocrit was significantly better than the control group(P<0.05)，the difference was statistically significant.Conclusion For cerebral thrombosis treated with low molecular weight heparin combined with sodium ozagrel treatment can effectively improve the laboratory parameters of patients，so as to improve the therapeutic effect，conducive to the rehabilitation of patients，which has clinical value.
, 百拇医药
Key words：Relatively low molecular weight heparin sodium；Ozagrel sodium；Cerebral thrombosis
脑血栓是临床常见的脑血管病变，发病机制与血液的粘稠性升高以及血小板的聚集有着很大的关系，脑血栓形成属于脑梗死疾病中最常见的类型，主要原因是脑动脉主干或皮质支动脉粥样硬化而引起的血管增厚、管腔狭窄闭塞以及血栓的形成，继而引起脑局部循环血流减少或供血中断，使得脑组织缺血缺氧最终出现软化和坏死，继而出现局灶性神经系统症状体征，因此，在临床上又将其称为“动脉粥样硬化性脑血栓”，多发生于50岁以后的人群，而且男性和多于女性，该病在临床上有着很高的致死率和致残率，临床上一般采用药物治疗以延缓疾病的发展，主要以降低血液的粘稠度为原则[1-2]。此次主要针对相对低分子质量肝素钠联合奥扎格雷钠治疗脑血栓形成的疗效展开评析，并做以下报道。, 百拇医药(孟宪普)
关键词：相对低分子质量肝素钠；奥扎格雷钠；脑血栓
中图分类号：R743.3 文献标识码：A 文章编号：1006-1959(2017)16-0083-02
, 百拇医药
Evaluation of Curative Effect of Relatively Low Molecular Weight Heparin Sodium Combined with Ozagrel in the Treatment of Cerebral Thrombosis
MENG Xian-pu
(2 Cases of Xinbin Manchu Autonomous County People's Hospital，Fushun 113200，Liaoning，China)
Abstract：Objective To evaluate on curative effect of low molecular weight heparin combined with sodium ozagrel in the treatment of cerebral thrombosis.Methods In April 2015～September 2016，as the research period，92 patients with cerebral thrombosis in this period were selected as the research object.They were randomly divided into the control group and the observation group，each with 46 cases，the control group was treated with conventional methods，the observation group with low molecular weight heparin combined with sodium ozagrel in treatment，comparison and analysis of two groups of patients and the results of laboratory examination.Results The total effective rate of observation group was 93.47%，control group total effective rate was 78.26%，there was a significant difference between the two groups(P<0.05)，which was statistically significant.The observation group of whole blood viscosity，plasma viscosity，platelet adhesion rate，total cholesterol and hematocrit was significantly better than the control group(P<0.05)，the difference was statistically significant.Conclusion For cerebral thrombosis treated with low molecular weight heparin combined with sodium ozagrel treatment can effectively improve the laboratory parameters of patients，so as to improve the therapeutic effect，conducive to the rehabilitation of patients，which has clinical value.
, 百拇医药
Key words：Relatively low molecular weight heparin sodium；Ozagrel sodium；Cerebral thrombosis
脑血栓是临床常见的脑血管病变，发病机制与血液的粘稠性升高以及血小板的聚集有着很大的关系，脑血栓形成属于脑梗死疾病中最常见的类型，主要原因是脑动脉主干或皮质支动脉粥样硬化而引起的血管增厚、管腔狭窄闭塞以及血栓的形成，继而引起脑局部循环血流减少或供血中断，使得脑组织缺血缺氧最终出现软化和坏死，继而出现局灶性神经系统症状体征，因此，在临床上又将其称为“动脉粥样硬化性脑血栓”，多发生于50岁以后的人群，而且男性和多于女性，该病在临床上有着很高的致死率和致残率，临床上一般采用药物治疗以延缓疾病的发展，主要以降低血液的粘稠度为原则[1-2]。此次主要针对相对低分子质量肝素钠联合奥扎格雷钠治疗脑血栓形成的疗效展开评析，并做以下报道。, 百拇医药(孟宪普)
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