脑卒中肥胖患者发病后血脂、血糖、血尿酸、同型半胱氨酸水平及血流动力学变化(1)
摘要：目的 探析脑卒中肥胖患者发病后血流动力学变化和血尿酸、血糖和血脂及同型半胱氨酸水平情况。方法 选取我院收治的脑卒中250例患者为研究资料，根据体质数将其分五组，即正常BMI组和中度肥胖组、轻度肥胖组和重度肥胖组及超重组，每组50例。对各组患者发病后的血液动力学和血尿酸、血糖和血脂及同行半胱氨酸水平指标情况进行检测。结果 除高密度脂蛋白外，正常BMI组的各项指标情况均比其余四组低(P<0.05)。伴随脑卒中患者BMI的上升，高密度脂蛋白水平不断下降，而各项指标水平除高密度脂蛋白外均呈上升趋势(P<0.05)。正常BMI组红细胞沉降率和全血低切黏度、血液粘度和血细胞比容及全血高切黏度最低(P<0.05)。在五组患者间，血压黏稠度各项指标和红细胞沉降率与血细胞比容情况，伴随BMI上升呈递增趋势(P<0.05)。结论 脑卒中肥胖者发病后，其同型半胱氨酸和血糖、血脂和血尿酸等指标均呈上升趋势，血流黏稠度提高，伴随BMI值的提高呈正相关关系。
关键词：血流动力学；血尿酸；血脂；同行半胱氨酸
, http://www.100md.com
中图分类号：R743.3 文献标识码：A 文章编号：1006-1959(2017)22-0186-02
Abstract：Objective The incidence of stroke patients with obesity after the change of hemodynamics and blood uric acid，blood glucose and blood lipid and homocysteine levels in stroke.Methods 250 cases in our hospital patients as the research data，according to the number of physical groups will be divided into five groups，namely，normal BMI group and moderate obesity group，mild obesity group and severe obesity group and overweight group，each group of 50 cases.The hemodynamics and blood uric acid，blood glucose and blood lipid and peptidyl cysteine levels were measured in each group.Results Except for high density lipoprotein，the indexes of normal BMI group were lower than those of the other four groups(P<0.05).With the rise of stroke patients with BMI，high density lipoprotein levels continue to decline，while the level of each index except high-density lipoprotein increased(P<0.05).Normal group BMI，erythrocyte sedimentation rate and low blood viscosity，blood viscosity and hematocrit and high blood viscosity is the lowest(P<0.05).Among the five groups，blood viscosity index and erythrocyte sedimentation rate and hematocrit，accompanied by a rise in BMI increased(P<0.05).Conclusion The indexes of homocysteine and blood glucose，blood lipid and serum uric acid were on the rise of obese subjects after stroke，and the blood viscosity increased with the increase of BMI.
, 百拇医药
Key words：Hemodynamics；Blood uric acid；Blood lipids；Peptidyl cysteine
腦卒中(cerebral stroke)在神经内科疾病中属于临床常见病症，易引发患者出现肢体活动不灵、意识障碍和呕吐恶心等病症表现。即便在治愈后脑卒中患者也会伴有不同程度的后遗症，劳动能力全部丧失或者部分丧失患者能达到75%左右。有研究报道显示[1]，对脑卒中患者而言，超重是导致此病症形成的主要机制，而且超重对动脉粥样硬化的发生能起到对应的推动作用，和动脉粥样硬化相互促进，从而易引发脑卒中病症的发生；但是现下临床对脑卒中患者病症严重程度是否和肥胖程度具有一定的关联性仍不确定。为探究脑卒中肥胖患者发病后血流动力学变化和血尿酸、血糖和血脂及同型半胱氨酸水平情况，现做出报道如下。
1资料与方法
1.1一般资料
选取2015年3月～2017年4月我院收治的脑卒中250例患者为本次研究资料，根据体质数将其分为正常BMI组和中度肥胖组、轻度肥胖组和重度肥胖组及超重组五组。正常BMI组50例，男28例，女22例；年龄42～64岁，平均年龄(57.3±2.1)岁。中度肥胖组50例，男29例，女21例；年龄43～66岁，平均年龄(59.2±2.2)岁。轻度肥胖组50例，男30例，女20例；年龄37～67岁，平均年龄(54.3±2.4)岁。重度肥胖组50例，男31例，女19例；年龄38～68岁，平均年龄(55.4±2.6)岁。超重组50例，男32例，女18例；年龄39～69岁，平均年龄(56.5±2.4)岁。把五组患者的临床资料情况对比(P>0.05)，组间数据资料情况可比较。, 百拇医药(江砚明 刘大洪)
关键词：血流动力学；血尿酸；血脂；同行半胱氨酸
, http://www.100md.com
中图分类号：R743.3 文献标识码：A 文章编号：1006-1959(2017)22-0186-02
Abstract：Objective The incidence of stroke patients with obesity after the change of hemodynamics and blood uric acid，blood glucose and blood lipid and homocysteine levels in stroke.Methods 250 cases in our hospital patients as the research data，according to the number of physical groups will be divided into five groups，namely，normal BMI group and moderate obesity group，mild obesity group and severe obesity group and overweight group，each group of 50 cases.The hemodynamics and blood uric acid，blood glucose and blood lipid and peptidyl cysteine levels were measured in each group.Results Except for high density lipoprotein，the indexes of normal BMI group were lower than those of the other four groups(P<0.05).With the rise of stroke patients with BMI，high density lipoprotein levels continue to decline，while the level of each index except high-density lipoprotein increased(P<0.05).Normal group BMI，erythrocyte sedimentation rate and low blood viscosity，blood viscosity and hematocrit and high blood viscosity is the lowest(P<0.05).Among the five groups，blood viscosity index and erythrocyte sedimentation rate and hematocrit，accompanied by a rise in BMI increased(P<0.05).Conclusion The indexes of homocysteine and blood glucose，blood lipid and serum uric acid were on the rise of obese subjects after stroke，and the blood viscosity increased with the increase of BMI.
, 百拇医药
Key words：Hemodynamics；Blood uric acid；Blood lipids；Peptidyl cysteine
腦卒中(cerebral stroke)在神经内科疾病中属于临床常见病症，易引发患者出现肢体活动不灵、意识障碍和呕吐恶心等病症表现。即便在治愈后脑卒中患者也会伴有不同程度的后遗症，劳动能力全部丧失或者部分丧失患者能达到75%左右。有研究报道显示[1]，对脑卒中患者而言，超重是导致此病症形成的主要机制，而且超重对动脉粥样硬化的发生能起到对应的推动作用，和动脉粥样硬化相互促进，从而易引发脑卒中病症的发生；但是现下临床对脑卒中患者病症严重程度是否和肥胖程度具有一定的关联性仍不确定。为探究脑卒中肥胖患者发病后血流动力学变化和血尿酸、血糖和血脂及同型半胱氨酸水平情况，现做出报道如下。
1资料与方法
1.1一般资料
选取2015年3月～2017年4月我院收治的脑卒中250例患者为本次研究资料，根据体质数将其分为正常BMI组和中度肥胖组、轻度肥胖组和重度肥胖组及超重组五组。正常BMI组50例，男28例，女22例；年龄42～64岁，平均年龄(57.3±2.1)岁。中度肥胖组50例，男29例，女21例；年龄43～66岁，平均年龄(59.2±2.2)岁。轻度肥胖组50例，男30例，女20例；年龄37～67岁，平均年龄(54.3±2.4)岁。重度肥胖组50例，男31例，女19例；年龄38～68岁，平均年龄(55.4±2.6)岁。超重组50例，男32例，女18例；年龄39～69岁，平均年龄(56.5±2.4)岁。把五组患者的临床资料情况对比(P>0.05)，组间数据资料情况可比较。, 百拇医药(江砚明 刘大洪)
参见：首页 > 医疗版 > 疾病专题 > 神经内科 > 脑血管病 > 中风(脑卒中)