补脾固贲汤联合康复新液治疗胃食管反流病的临床观察(1)
摘要：目的 观察补脾固贲汤联合康复新液治疗胃食管反流病临床疗效。方法 回顾分析2016年6月～2017年6月在我院诊治的92例胃食管反流病患者临床资料，将其随机分为对照组和观察组，每组46例。对照组患者采用康复新液治疗，观察组在对照组治療基础上加服补脾固贲汤，观察对比两组患者临床治疗疗效。结果 观察组治疗总有效率明显高于对照组，差异有统计学意义(P<0.05)；治疗后观察组临床症状(烧心、反酸、嗳气、疼痛)评分明显低于对照组，差异有统计学意义(P<0.05)；观察组生活质量明显高于对照组，差异有统计学意义(P<0.05)；在治疗和观察期间，两组均未发生严重不良反应，两组对比差异无统计学意义(P>0.05)。结论 补脾固贲汤联合康复新液治疗胃食管反流病疗效理想，可显著改善患者临床症状，且无严重不良反应，用药安全，值得临床推广和应用。
关键词：补脾固贲汤；康复新液；胃食管反流病
中图分类号：R259 文献标识码：A 文章编号：1006-1959(2017)22-0081-02
, 百拇医药
Abstract：Objective To observe the effect of nourishing spleen and Bi decoction combined with Kangfuxin liquid in treatment of gastroesophageal reflux disease patients.Methods Retrospective analysis of June 2016～2017 in June in the 92 cases of gastroesophageal reflux disease in patients with clinical data in our hospital，they were randomly divided into control group and observation group，46 cases in each group.The control group were treated with Kangfuxin solution treatment，the observation group in the control group treated with taking nourishing spleen and Bi decoction，observe comparison of two groups of patients with clinical curative effect.Results The total efficiency of the observation group was significantly higher than the control group，the difference was statistically significant(P<0.05)；after treatment，clinical symptoms(heartburn，acid regurgitation，belching，pain)was significantly lower than the control group，the difference was statistically significant(P<0.05)；quality of life in the observation group was significantly higher than the control group，the difference was statistically significant(P<0.05)；during the period of treatment and observation，the two groups had no serious adverse reactions，no significant differences between the two groups(P>0.05).Conclusion Nourishing spleen and Bi decoction combined with Kangfuxin liquid in treatment of gastroesophageal reflux disease with ideal curative effect，can significantly improve the clinical symptoms of patients， and no serious adverse reactions，drug safety，and is worthy of clinical promotion and application.
, http://www.100md.com
Key words：Nourishing spleen and Bi decoction；Kangfuxin liquid；Gastroesophageal reflux disease
随着生活水平的提高，人们的饮食结构发生变化，胃食管反流病发生率不断上升[1]。该疾病是临床常见疾病，是胃十二指肠内容物反流入食管引起烧灼感等症状，严重影响患者的身体健康，并且对患者的工作和心理会造成一定的负担。该疾病的发生由多种因素造成，主要发病机制是抗反流防御机制减弱和反流物对食管黏膜攻击作用的结果。临床通常采用西药治疗，随着传统中医学在临床的广发应用，在治疗胃食管反流病方面取得了一定的疗效。本文作者结合2016年6月～2017年6月在我院诊治的92例胃食管反流病患者临床资料，补脾固贲汤联合康复新液治疗胃食管反流病临床效果，现报告如下。
1资料与方法
1.1一般资料
回顾分析2016年6月～2017年6月在我院诊治的92例胃食管反流病患者临床资料，将其随机分为对照组和观察组，每组46例。对照组中，男性25例，女性21例；年龄24～68岁，平均年龄(45.12±9.05)岁；病程2个月～3年，平均病程(8.98±1.20)个月。对照组中，男性24例，女性22例；年龄25～68岁，平均年龄(44.78±8.65)岁；病程2个月～3年，平均病程(9.01±1.55)个月。两组患者在年龄、性别、病程等基础资料方面差异无统计学意义(P>0.05)。, http://www.100md.com(潘应芳)
关键词：补脾固贲汤；康复新液；胃食管反流病
中图分类号：R259 文献标识码：A 文章编号：1006-1959(2017)22-0081-02
, 百拇医药
Abstract：Objective To observe the effect of nourishing spleen and Bi decoction combined with Kangfuxin liquid in treatment of gastroesophageal reflux disease patients.Methods Retrospective analysis of June 2016～2017 in June in the 92 cases of gastroesophageal reflux disease in patients with clinical data in our hospital，they were randomly divided into control group and observation group，46 cases in each group.The control group were treated with Kangfuxin solution treatment，the observation group in the control group treated with taking nourishing spleen and Bi decoction，observe comparison of two groups of patients with clinical curative effect.Results The total efficiency of the observation group was significantly higher than the control group，the difference was statistically significant(P<0.05)；after treatment，clinical symptoms(heartburn，acid regurgitation，belching，pain)was significantly lower than the control group，the difference was statistically significant(P<0.05)；quality of life in the observation group was significantly higher than the control group，the difference was statistically significant(P<0.05)；during the period of treatment and observation，the two groups had no serious adverse reactions，no significant differences between the two groups(P>0.05).Conclusion Nourishing spleen and Bi decoction combined with Kangfuxin liquid in treatment of gastroesophageal reflux disease with ideal curative effect，can significantly improve the clinical symptoms of patients， and no serious adverse reactions，drug safety，and is worthy of clinical promotion and application.
, http://www.100md.com
Key words：Nourishing spleen and Bi decoction；Kangfuxin liquid；Gastroesophageal reflux disease
随着生活水平的提高，人们的饮食结构发生变化，胃食管反流病发生率不断上升[1]。该疾病是临床常见疾病，是胃十二指肠内容物反流入食管引起烧灼感等症状，严重影响患者的身体健康，并且对患者的工作和心理会造成一定的负担。该疾病的发生由多种因素造成，主要发病机制是抗反流防御机制减弱和反流物对食管黏膜攻击作用的结果。临床通常采用西药治疗，随着传统中医学在临床的广发应用，在治疗胃食管反流病方面取得了一定的疗效。本文作者结合2016年6月～2017年6月在我院诊治的92例胃食管反流病患者临床资料，补脾固贲汤联合康复新液治疗胃食管反流病临床效果，现报告如下。
1资料与方法
1.1一般资料
回顾分析2016年6月～2017年6月在我院诊治的92例胃食管反流病患者临床资料，将其随机分为对照组和观察组，每组46例。对照组中，男性25例，女性21例；年龄24～68岁，平均年龄(45.12±9.05)岁；病程2个月～3年，平均病程(8.98±1.20)个月。对照组中，男性24例，女性22例；年龄25～68岁，平均年龄(44.78±8.65)岁；病程2个月～3年，平均病程(9.01±1.55)个月。两组患者在年龄、性别、病程等基础资料方面差异无统计学意义(P>0.05)。, http://www.100md.com(潘应芳)
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