硝酸甘油联合阿司匹林治疗心绞痛的临床效果观察(1)
摘 要：目的 分析硝酸甘油联合阿司匹林治疗心绞痛的疗效和价值。方法 选取2016年1月～2017年1月我院接收的心绞痛患者86例，随机分为对照组和观察组各43例。对照组应用硝酸甘油治疗，观察组应用硝酸甘油联合阿司匹林治疗。统计两组患者用药后的每日心绞痛频率、每日硝酸甘油用量、心电图缺血时间、心电图缺血次数，观察临床疗效、心电图疗效不良反应发生情况。结果 观察组治疗总有效率(97.67%)高于对照组(76.74%)，差异有统计学意义(P<0.05)；观察组心电图明显改善率(48.84%)明显高于对照组(32.56%)，差异有统计学意义(P<0.05)；观察组每日心绞痛次数、硝酸甘油用量、心电图缺血时间、心电图缺血次数均优于对照组，两组差异有统计学意义(P<0.05)。两组患者的不良反应发生率差异无统计学意义(P>0.05)。结论 对心绞痛患者采用硝酸甘油联合阿司匹林治疗，可获得较好的治疗效果，值得临床应用及推广。
关键词：心绞痛；硝酸甘油；阿司匹林
中图分类号：R541.4 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.02.043
, 百拇医药
文章编号：1006-1959(2018)02-0119-03
Abstract：Objective To analyze the efficacy and value of nitroglycerin combined with aspirin in the treatment of angina pectoris.Methods From January 2016 to January 2017，86 patients with angina pectoris admitted to our hospital were randomly divided into control group and observation group，with 43 cases in each group.The control group was treated with nitroglycerin，and the observation group was treated with nitroglycerin combined with aspirin.The daily angina frequency， the amount of nitroglycerin daily，the time of electrocardiogram ischemia，the times of electrocardiogram ischemia， and the clinical curative effect and electrocardiogram curative effect were analyzed.Results The total effective rate(97.67%)in the observation group was significantly higher than that in the control group(76.74%)，the difference was statistically significant(P<0.05)；The significant improvement rate of electrocardiogram(48.84%)in observation group was significantly higher than that of control group(32.56%)，the difference was statistically significant(P<0.05).The number of angina pectoris， nitroglycerin， electrocardiogram ischemia time and electrocardiogram ischemia in observation group were all better than those in control group.There was significant difference between the two groups(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The treatment of angina patients with nitroglycerin combined with aspirin，can get better therapeutic effect，it is worth clinical application and promotion.
, 百拇医药
Key words：Angina；Nitroglycerin；Aspirin
心絞痛(angina pectoris)是临床上较常见的心内科疾病，临床表现为左胸前、胸骨后侧疼痛，随着病情发展，疼痛会逐渐扩散到手指、左肩、左臂等部位。从发病机制来看，心绞痛多是由于冠状动脉供血不足致使心肌缺血、心脏血液供给不足所引发，一般给予血管扩张剂可有效缓解患者的病症表现[1]。硝酸甘油、阿司匹林都是血管扩张剂的常见药物，为进一步探讨其疗效，本文以2016年1月～2017年1月间我院接收的心绞痛患者86例为研究对象，对其治疗资料进行了回顾性分析，报告如下。
1资料与方法
1.1一般资料 选取2016年1月～2017年1月我院接收的心绞痛患者86例为研究对象。所有程序通过医院伦理委员会审核，患者及其家属均知情同意。将患者随机分为观察组和对照组，各43例。观察组男22例，女21例，年龄55～88岁，平均年龄(70.3±2.2)岁；病程1～10年，平均病程(5.5±1.7)年；其中梗死后心绞痛3例，卧位型心绞痛9例，自发性心绞痛10例，恶化型劳力性心绞痛8例，劳累性心绞痛5例，初发劳力性心绞痛8例。对照组男23例，女20例，年龄58～87岁，平均年龄(68.9±2.0)岁；病程1～9年，平均病程(5.6±1.5)年；其中梗死后心绞痛2例，卧位型心绞痛10例，自发性心绞痛11例，恶化型劳力性心绞痛9例，劳累性心绞痛4例，初发劳力性心绞痛7例。两组患者在一般资料上差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(张文魁)
关键词：心绞痛；硝酸甘油；阿司匹林
中图分类号：R541.4 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.02.043
, 百拇医药
文章编号：1006-1959(2018)02-0119-03
Abstract：Objective To analyze the efficacy and value of nitroglycerin combined with aspirin in the treatment of angina pectoris.Methods From January 2016 to January 2017，86 patients with angina pectoris admitted to our hospital were randomly divided into control group and observation group，with 43 cases in each group.The control group was treated with nitroglycerin，and the observation group was treated with nitroglycerin combined with aspirin.The daily angina frequency， the amount of nitroglycerin daily，the time of electrocardiogram ischemia，the times of electrocardiogram ischemia， and the clinical curative effect and electrocardiogram curative effect were analyzed.Results The total effective rate(97.67%)in the observation group was significantly higher than that in the control group(76.74%)，the difference was statistically significant(P<0.05)；The significant improvement rate of electrocardiogram(48.84%)in observation group was significantly higher than that of control group(32.56%)，the difference was statistically significant(P<0.05).The number of angina pectoris， nitroglycerin， electrocardiogram ischemia time and electrocardiogram ischemia in observation group were all better than those in control group.There was significant difference between the two groups(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The treatment of angina patients with nitroglycerin combined with aspirin，can get better therapeutic effect，it is worth clinical application and promotion.
, 百拇医药
Key words：Angina；Nitroglycerin；Aspirin
心絞痛(angina pectoris)是临床上较常见的心内科疾病，临床表现为左胸前、胸骨后侧疼痛，随着病情发展，疼痛会逐渐扩散到手指、左肩、左臂等部位。从发病机制来看，心绞痛多是由于冠状动脉供血不足致使心肌缺血、心脏血液供给不足所引发，一般给予血管扩张剂可有效缓解患者的病症表现[1]。硝酸甘油、阿司匹林都是血管扩张剂的常见药物，为进一步探讨其疗效，本文以2016年1月～2017年1月间我院接收的心绞痛患者86例为研究对象，对其治疗资料进行了回顾性分析，报告如下。
1资料与方法
1.1一般资料 选取2016年1月～2017年1月我院接收的心绞痛患者86例为研究对象。所有程序通过医院伦理委员会审核，患者及其家属均知情同意。将患者随机分为观察组和对照组，各43例。观察组男22例，女21例，年龄55～88岁，平均年龄(70.3±2.2)岁；病程1～10年，平均病程(5.5±1.7)年；其中梗死后心绞痛3例，卧位型心绞痛9例，自发性心绞痛10例，恶化型劳力性心绞痛8例，劳累性心绞痛5例，初发劳力性心绞痛8例。对照组男23例，女20例，年龄58～87岁，平均年龄(68.9±2.0)岁；病程1～9年，平均病程(5.6±1.5)年；其中梗死后心绞痛2例，卧位型心绞痛10例，自发性心绞痛11例，恶化型劳力性心绞痛9例，劳累性心绞痛4例，初发劳力性心绞痛7例。两组患者在一般资料上差异无统计学意义(P>0.05)，具有可比性。, 百拇医药(张文魁)