醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者的疗效分析(1)
摘要：目的 分析醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者治疗效果。方法 选取我院2015年1月～2017年10月中收治脑出血后昏迷患者68例作为研究对象，随机分为参照组和联合组，每组34例。参照组在常规治疗上加盐酸纳洛酮，联合组在参照组的基础上加用醒脑静配合治疗，将两组GCS分值与脑血肿量变化及NIHSS评分情况进行比较。结果 治疗后联合组的GCS分值(14.24±2.05)分与脑血肿量(17.41±2.44)ml明显优于参照组的(9.87±1.62)分和(25.50±2.42)ml，差异有统计学意义(P<0.05);联合组在出院后3个月的NIHSS评分情况(10.01±1.95)分优于参照组(12.50±2.31)分，差异有统计学意义(P<0.05)。结论 采用醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者可显著改善脑出血患者的意识障碍，促进神经功能恢复，减轻脑部水肿情况，改善患者临床疗效。
关键词：醒脑静;盐酸纳洛酮;脑出血后昏迷
中图分类号：R743.34 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.06.050
, 百拇医药
文章编号：1006-1959(2019)06-0157-03
Abstract：Objective To analyze the therapeutic effect of Xingnaojing combined with naloxone hydrochloride in the treatment of coma patients with cerebral hemorrhage. Methods A total of 68 patients with coma after cerebral hemorrhage were enrolled in our hospital from January 2015 to October 2017. They were randomly divided into reference group and combined group， with 34 cases in each group. In the reference group， naloxone hydrochloride was added to the conventional treatment， and the combined group was treated with Xingnaojing on the basis of the reference group. The GCS scores of the two groups were compared with the changes of cerebral hematoma volume and NIHSS score. Results After treatment， the GCS score (14.24±2.05) and cerebral hematoma volume (17.41±2.44) ml were significantly better than the reference group (9.87±1.62) and (25.50±2.42) ml，the difference was statistically significant (P<0.05); The NIHSS score (10.01±1.95) in the combined group was better than the reference group (12.50±2.31) at 3 months after discharge，the difference was statistically significant (P<0.05). Conclusion The treatment of coma after cerebral hemorrhage with Xingnaojing combined with naloxone hydrochloride can significantly improve the disturbance of consciousness in patients with cerebral hemorrhage， promote the recovery of nerve function， reduce the edema of the brain and improve the clinical efficacy of patients.
Key words：Xingnaojing;Naloxone hydrochloride;Coma after cerebral hemorrhage
腦出血(intracerebral hemorrhage)是一种临床常见的意外性疾病，患者在昏迷状态下，发作疾病时具有迅速、病情严重、致残率及病死率高的特点[1]。当前在临床上对于脑出血患者一般采用保守治疗或者手术治疗，但是这两种治疗方法均要结合患者的实际病情进行治疗，有研究表明，醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者具有显著疗效[2]，为此本次研究采用醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者对其治疗效果进行研究分析。, http://www.100md.com(刘永刚 张学勇)
关键词：醒脑静;盐酸纳洛酮;脑出血后昏迷
中图分类号：R743.34 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.06.050
, 百拇医药
文章编号：1006-1959(2019)06-0157-03
Abstract：Objective To analyze the therapeutic effect of Xingnaojing combined with naloxone hydrochloride in the treatment of coma patients with cerebral hemorrhage. Methods A total of 68 patients with coma after cerebral hemorrhage were enrolled in our hospital from January 2015 to October 2017. They were randomly divided into reference group and combined group， with 34 cases in each group. In the reference group， naloxone hydrochloride was added to the conventional treatment， and the combined group was treated with Xingnaojing on the basis of the reference group. The GCS scores of the two groups were compared with the changes of cerebral hematoma volume and NIHSS score. Results After treatment， the GCS score (14.24±2.05) and cerebral hematoma volume (17.41±2.44) ml were significantly better than the reference group (9.87±1.62) and (25.50±2.42) ml，the difference was statistically significant (P<0.05); The NIHSS score (10.01±1.95) in the combined group was better than the reference group (12.50±2.31) at 3 months after discharge，the difference was statistically significant (P<0.05). Conclusion The treatment of coma after cerebral hemorrhage with Xingnaojing combined with naloxone hydrochloride can significantly improve the disturbance of consciousness in patients with cerebral hemorrhage， promote the recovery of nerve function， reduce the edema of the brain and improve the clinical efficacy of patients.
Key words：Xingnaojing;Naloxone hydrochloride;Coma after cerebral hemorrhage
腦出血(intracerebral hemorrhage)是一种临床常见的意外性疾病，患者在昏迷状态下，发作疾病时具有迅速、病情严重、致残率及病死率高的特点[1]。当前在临床上对于脑出血患者一般采用保守治疗或者手术治疗，但是这两种治疗方法均要结合患者的实际病情进行治疗，有研究表明，醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者具有显著疗效[2]，为此本次研究采用醒脑静联合盐酸纳洛酮治疗脑出血后昏迷患者对其治疗效果进行研究分析。, http://www.100md.com(刘永刚 张学勇)