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驱白巴布期片治疗寻常型白癜风临床疗效观察(1)
http://www.100md.com 2011年9月1日 刘彦婷 曾维惠 王军文 张洪冰
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     [摘要]目的:观察驱白巴布期片治疗寻常型白癜风的临床疗效。方法:门诊收集887例白癜风患者,随机分为两组:治疗组445例,给予口服驱白巴布期片;对照组442例,给予口服甲氧沙林片,两组均联合外用复方卡力孜然酊及卤米松。两组均连续治疗6个月,分别于2、4、6个月进行临床疗效和不良反应的评价。结果:治疗组445例和对照组442例总有效率分别为77.5%和61.8%;治疗组内病程<1年组及病程>1年组的有效率分别为93.5%和73.2%;对照组内病程<1年组及病程>1年组的有效率分别为78.2%和56.7%。以上三组数据经检验均具有统计学差异。同时,治疗组和对照组在治疗2、4、6个月后产生色素的皮损片数具有统计学差异。结论:驱白巴布期片治疗组的临床疗效明显优于对照组,两组患者均无严重不良反应发生,驱白巴布期片治疗白癜风疗效确切,安全性好。

    [关键词]白癜风;驱白巴布期片;临床疗效

    [中图分类号]R758.4+1 [文献标识码]A[文章编号]1008-6455(2011)09-1428-03

    Clinical efficacy of the Qubai Babuqi Tablets in the treatment of vitiligo

    LIU Yan-ting,ZENG Wei-hui,WANG Jun-wen,ZHANG Hong-bing

    (1.Department of Dermatology,The Second Affiliated Hospital,Xi'an Jiaotong University,Xi'an 710004,Shaanxi,China;2.Department of Dermatology,The Second Affiliated Hospital,Hunan University of Traditional Chinese Medicine,Changsha 410005,Hunan,China;3.Department of Dermatology,Vitiligo Research Institute of Shandong University,Ji'nan 250002,Shandong,China)

    Abstract:ObjectiveTo investigate the clinical efficacy of the Qubai Babuqi Tablets in the treatment of vitiligo. Methods887 patients were randomly divided into 2 groups. The treatment group were 445 cases,which received oral administration of Qubai Babuqi Tablets,while the control group were 442 cases,which received oral administration of methoxsalen pellet,and both of the two groups combing with theFufang Kaliziran Ding and Halometasone cream for 6 months. Investigate the clinical efficacy after 2,4,6 months respectively. ResultsTotal effective rate of the treatment group was 77.5% and the control group was 61.8%.The efficiency was improved obviously compared with the control group. Conclusion Qubai babuqi tablets is effective in the treatment of vitiligo and therefore deserves further clinical applications。

    Key words:vitiligo;Qubai Babuqi Tablets;clinical efficacy

    白癜风是一种获得性色素脱失性皮肤病,发病机制尚不清楚,易诊难治[1]。笔者于2008年12月~2010年12月采用驱白巴期布片联合外用复方卡力孜然酊及卤米松治疗寻常型白癜风患者,取得了显著疗效,现报道如下。

    1临床资料

    1.1 一般资料:选择寻常型稳定期白癜风门诊患者共887例,包括局限型、散发型、泛发型和肢端型,随机分为两组。驱白巴布期片治疗组445例,男202例,女243例。年龄18~60岁,平均38岁。病程1个月~35年,平均8.3年;病程<1年109例,病程>1年336例,皮损共 1 303片,治疗方案为口服驱白巴布期片联合外用复方卡力孜然酊及卤米松;对照组442例,男222例,女220例,年龄18~60岁 ......

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