论文下载：红藤愈萎养胃汤对胃癌前病变血清胃癌相关抗原MG7、胃蛋白酶原

红藤愈萎养胃汤对胃癌前病变血清胃癌相关抗原MG7、胃蛋白酶原表达的影响(1)

http://www.100md.com 2012年1月1日马伟明陈笑腾康年松陈振浩岑迎东杜玉琳高望望

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     摘要：目的：研究红藤愈萎养胃汤对慢性萎缩性胃炎(CAG)伴胃癌前病变患者血清胃癌相关抗原MG7(sMG7-Ag)、胃蛋白酶原(sPG)表达的影响。方法：用随机表法将90例患者分为西药组(n=30)、胃复春组(n=30)和红藤愈萎养胃汤组(n=30)，检测治疗前、治疗30天及治疗60天后sMG7-Ag、sPGI和sPGII水平。结果：①治疗前红藤愈萎养胃汤组sMG7-Ag (136.50±54.60)ng/L，sPGI (121.74±26.31)μg/L，sPGII (25.40±5.08)μg/L，sPGI/sPGII (4.80± 0.52)；②治疗30天后红藤愈萎养胃汤组sMG7-Ag (135.47±53.24)ng/L，sPGI (159.55±19.27)μg/L，sPGII (26.63± 4.45)μg/L，sPGI/sPGII (6.05±0.52)；③治疗60天红藤愈萎养胃汤组sMG7-Ag (130.48± 49.01)ng/L，sPGI (188.90±14.17)μg/L，sPGII (29.07±4.41)μg/L，sPGI/sPGII (6.58±0.67)。结论：红藤愈萎养胃汤能提高CAG伴癌前病变患者sPGI、sPGII以及sPGI/sPGII，但尚不能显著降低sMG7-Ag。

    关键词：红藤愈萎养胃汤；萎缩性胃炎；胃癌前病变；胃癌相关抗原；胃蛋白酶原

    中图分类号：R285.5 文献标识码：B 文章编号：1673-7717(2012)01-0070-03

    Effect of Hongteng Yuwei Yangwei Decoction on Serum Expression of Gastric Cancer-

    associated Antigen MG7 and Pepsinogen of Gastric Precancerosis

    MA Weiming,CHEN Xiaoteng,KANG Niansong,CHEN Zhenhao,CEN Yingdong,DU Yulin,GAO Wangwang.

    (Yuyao Traditional Chinese Medicine Hospital,Yuyao 315400，Zhejiang，China)

    Abstract:Objective:To study effect of Hongteng Yuwei Yangwei decoction on serum expression of gastric cancer-associated antigen MG7(sMG7-Ag) and pepsinogen(sPG) of chronic atrophic gastritis(CAG) with gastric precancerosis.Methods:90 patients were divided into western medicine group(n=30),Weifuchun group(n=30) and Hongteng Yuwei Yangwei group(n=30) by method of random number. sMG7-Ag, sPGI, sPGII and sPGI/sPGII were tested before treatment, and after 30-day and 60-day treatment.Results:①sMG7-Ag of Hongteng Yuwei Yangwei group before treatment was (136.50±54.60)ng/L, sPGI (121.74±26.31)μg/L, sPGII (25.40±5.08)μg/L and sPGI/sPGII (4.80±0.52). ②sMG7-Ag of Hongteng Yuwei Yangwei group after 30-day treatment was (135.47±53.24)ng/L, sPGI (159.55±19.27)μg/L, sPGII (26.63±4.45)μg/L and sPGI/sPGII (6.05±0.52).③sMG7-Ag of Hongteng Yuwei Yangwei group after 60-day treatment was (130.48±49.01)ng/L, sPGI (188.90±14.17)μg/L, sPGII (29.07±4.41)μg/L, sPGI/sPGII (6 ......

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