基质金属蛋白酶及其抑制物在慢性阻塞性肺疾病中的相关研究(3)
[11] Abboud RT,Wallace AM,English JC,et al.Relationship of matrix met-alloproteinase mRNA expression and genetic polymorphisms to em physema[J].Proc Am Thorac Soc,2006,3(6):475.
[12] Saitoh W，Sakamoto T,Hegab AE，et al.MMP14 gene polymorphisms in chronic obstructive pulmonary disease[J].Int J Mol Med,2006,17(4):621.
[13] Lagente V,Manoury B,Nenan S,et al.Role of matrix metalloproteina-ses in the development of airyway inflammation and remodeling[J].Braz J Med Biol Res,2005,38(10):1521.
[14] Hirano K,Sakamoto T,Uchida Y,et al.Tissue inhibitor of metallopr-oteinases-2 gene polymorphisms in chronic obstructive pulmonary dis ease[J].Eur Respir J,2001,18(5):748.
[15] Pons AR，Sauleda J,Noguera A,et al.Decreased macrophage release of TGF-βand TIMP-1 in chronic obstructive pulmonary disease[J].Eur Respir J,2005,26(1):60.
[16] Mercer PF,Shute JK,Bhowmik A，et al.MMP-9,TIMP-1 and inflam-matory cells in sputum from COPD patients during exacerbation[J].Respir Res,2005,6:151.
[17] Higashimoto Y,Yamagata Y,Iwata T,et al.Increased serum concentr-ations of tissue inhibitor of metalloproteinase-1 in COPD patients[J].Eur Respir J,2005,25(5):885.
收稿日期：2007-07-26 修回日期：2007-08-02, http://www.100md.com(段 珊 邓立普)
[12] Saitoh W，Sakamoto T,Hegab AE，et al.MMP14 gene polymorphisms in chronic obstructive pulmonary disease[J].Int J Mol Med,2006,17(4):621.
[13] Lagente V,Manoury B,Nenan S,et al.Role of matrix metalloproteina-ses in the development of airyway inflammation and remodeling[J].Braz J Med Biol Res,2005,38(10):1521.
[14] Hirano K,Sakamoto T,Uchida Y,et al.Tissue inhibitor of metallopr-oteinases-2 gene polymorphisms in chronic obstructive pulmonary dis ease[J].Eur Respir J,2001,18(5):748.
[15] Pons AR，Sauleda J,Noguera A,et al.Decreased macrophage release of TGF-βand TIMP-1 in chronic obstructive pulmonary disease[J].Eur Respir J,2005,26(1):60.
[16] Mercer PF,Shute JK,Bhowmik A，et al.MMP-9,TIMP-1 and inflam-matory cells in sputum from COPD patients during exacerbation[J].Respir Res,2005,6:151.
[17] Higashimoto Y,Yamagata Y,Iwata T,et al.Increased serum concentr-ations of tissue inhibitor of metalloproteinase-1 in COPD patients[J].Eur Respir J,2005,25(5):885.
收稿日期：2007-07-26 修回日期：2007-08-02, http://www.100md.com(段 珊 邓立普)