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编号:11976903
缺血性卒中病因分型法在中国卒中人群应用效果的比较(1)
http://www.100md.com 2010年4月1日 韩 钊,臧秋玲,王苹莉,肖美娟,叶祖森
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     中图分类号:R743 文献标识码 :A 文章编号:1009_816X(2010)02_0088_03

    Comparative Study of Two Etiological Classifications of Ischemic Stro ke in Chinese Stroke Patients.HAN Zhao, ZANG Qiu_ling, WANG Ping_li, et al.Division of S troke Medicine, First Affiliated Hospital, Wenzhou Medical College, Zhejiang 325 000, China

    [Abstract] ObjectiveTo evaluate inter_investigator agreement between TOAST Clas sification proposed by Adams et al in 1993 and a new Classification proposed bySang Won Han et al in 2007 and to study the difference of the proportion for eac h subtype in Chinese ischemic stroke patients diagnosed by the two Classificatio ns respectively.Methods395 Consecutive cases with acute ischemic stroke were e nrolled in this study, their etiological subtypes were diagnosed at discharge byone neurologist according to the two Classifications and χ2 test was used tocompare the difference of the proportion for each subtype. Meanwhile,two neuro logists independently diagnosed subtype of 20 cases selected randomly and Kappaanalysis was used to evaluate inter_investigators agreement.Results(1) Two inves tigators have agreement with the stroke subtype diagnosis in 17 out of 20 casesby TOAST criteria (k=0.78) and in 18 out of 20 cases by Sang Won Han et al newc lassification system(k=0.93). (2) According to TOAST classification, the consti t uent ratio of subtypes for all enrolled cases was as following: stroke of undete rmined etiology 39.0%, Small_artery disease 29.6%, Large_artery atherosclerosi s21.3%, cardioembolism 8.9%, Stroke of other determined cause 1.3%; By the newcl assification system of Sang Won Han, the constituent ratio subtypes was as follo wing: atherothrombosis 44.6%, Stroke of undetermined etiology 25.1%, small_art ery disease 23.3%, cardioembolism 5.8%, stroke of other determined cause 1.3% . ConclusionsBoth of the two classifications have excellent agreement ......

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