中图分类号：R743.3

    文献标 识码：A

    文章编号：1009_816X(2011)05_0353_04

    DOI:10.3969/j.issn.1009_816X.2011.05.08

    With Severe Middle Cerebral Artery Stenosis Attributed to Atheroscler osis. ZHENG Jin_hua， ZANG Qiu_ling， SHAO Bei， et al. First People' s Hospital of Wenling City, Zhejiang 317500， China

    [Abstract] Objective To explore the risk factors attributed toatherosclerosis in patients with acute ischemic stroke with severe middle cereb ral artery stenosis. MethodsWe consecutively collected retrospectively the clinical data of patient s with acute ischemic stroke stay at the First Affiliated Hospital of Wenzhou Me dical College from February 2007 to January 2010.We classified the patients withboth concomitant perforator and pial or border_zone infarcts and stenosis ≥70 % of related middle cerebral artery as the case group, and the patients with sin gle perforator infarct with diameter ≤3.20cm and the related cerebral artery w ithout stenosis and the stenosis ≤30% of related carotid as control group. Wecompared the risk factors of the two groups with single factor analysis and non_ conditional logistic regression analysis.Results 189 cases were enrolled, with51 patients in case group and 138 cases in control group. The independent variab les associated with the moderate stenosis attributed to atherosclerosis in acuteischemic stroke were high density lipoprotein(OR=2.62 ......