糖尿病性眼肌麻痹患者糖代谢和脂代谢变化的分析(1)
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[摘要] 目的:探讨糖尿病性眼肌麻痹患者血糖(PBG)、糖化血红蛋白(HbA1c)与血脂变化之间的关系。方法:对36例糖尿病性眼肌麻痹患者和36例健康对照者进行隔夜空腹12 h血HbA1c、空腹血糖(FBG)、餐后2 h PBG、血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)检测,并进行相关性分析。结果:糖尿病性眼肌麻痹组HbA1c、FBG、PBG、TC、TG、LDL-C水平显著增高,HDL-C水平显著降低,与健康对照组相比较差异均有统计学意义(P<0.01)。糖尿病性眼肌麻痹组HbA1c与FBG、PBG呈正相关,与TC、TG存在平行升高趋势。结论:高血糖、高血脂是糖尿病并发周围神经病变的危险因素,控制血糖、改善脂代谢异常对预防和治疗糖尿病并发周围神经病变有指导意义。
[关键词] 糖尿病性眼肌麻痹； 糖基化血红蛋白； 血脂； 血糖
[中图分类号] R587.2 [文献标识码] A [文章编号] 1671-7256(2011)02-0125-04
doi：10.3969/j.issn.1671-7256.2011.02.002
Change and significance of blood glucose metabolism and plasma lipid
metabolism in patients with diabetic ocular muscles palsy
YAO Xiang-rong1, ZHANG Quan-hua2, L Yun-li1, ZHAO Bo1, LIAO Jun1,LIU Ji-yao1, JIA Cun-wei1
(1. Department of Neurology, 2. Department of Clinical Laboratory, Anning Branch of Lanzhou General Hospital
of Lanzhou Military Command of PLA, Lanzhou 730070, China)
[Abstract] Objective: To investigate the correlation between the change of the blood glucose, glycosylated hemoglobin 1c(HbA1c) and plasma lipid levels of patients with diabetic ocular muscles palsy. Methods: Venous blood samples were collected from 36 patients with diabetic ocular muscles palsy and 36 healthy controls(healthy control group). The HbA1c,fasting blood glucose(FBG), postprandial blood glucose(FBG), total cholesterol(CH), triglycerides(TG), high-density lipoprotein cholesterol(HDL-C), and low-density lipoprotein cholesterol(LDL-C) were measured after fasting for 12 h. The correlation analysis was performed between blood glucose, HbA1c and plasma lipid levels in the two group. Results: The levels of plasma FBG, P2BG, HbA1c, TC, TG, and LDL-C were significantly higher in diabetic ocular muscles palsy group than healthy control group(P<0.01). The levels of plasma HDL-C were significantly lower in diabetic ocular muscles palsy group than healthy control group(P<0.01). There was a positive correlation between HbA1c and FBG, PBG ......
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