摘要：目的：对将四联疗法应用于难治性消化性溃疡的临床应用效果进行观察和分析。方法：将在我院接受治疗的难治性消化性溃疡患者分为两组，共计46例，分别划分为对照组和观察组两组，对照组应用三联疗法，观察组应用四联疗法，对治疗情况进行比较和分析。结果：观察组患者的临床治疗有效率显著高于对照组，幽门螺旋杆菌根除率明显高于对照组，两组均具有显著差异(P<0.05)。结论：四联用药能有效根除幽门螺旋杆菌感染，促进溃疡的愈合，对难治性消化性溃疡疗效显著。

    关键词：难治性消化性溃疡四联治疗临床疗效

    Doi:10.3969/j.issn.1671-8801.2014.07.023Treatment with intractable peptic ulcer quadruple therapy effect is discussed in this paper

    Yang Zili

    Abstract:Objective:To the clinical application effect of quadruple therapy for refractory peptic ulcer was observed and analyzed.Methods:In our hospital were refractory peptic ulcer patients were divided into two groups ......