冠心胶囊对冠心病介入术后患者血清胱抑素C及尿β2-微球蛋白的影响(1)
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摘要：目的 观察冠心胶囊对冠心病介入术后患者肾功能指标血清胱抑素C(Cys C)及尿β2-微球蛋白(β2-MG)水平的影响。方法 将64例患者随机分为治疗组、对照组，各32例，两组疗程均为7 d，疗程结束后评定疗效。结果 治疗组与对照组比较，患者Cys C、尿β2-MG水平在治疗前、介入后48 h无统计学意义(P>0.05)；而在介入后7 d，Cys C水平治疗组为(0.86±0.14) g/L明显低于对照组(0.94±0.29) g/L(P<0.01)，尿β2-MG水平治疗组为(0.19±0.16) g/L明显低于对照组(0.33±0.27) g/L(P<0.01)。结论 冠心胶囊能明显降低Cys C、尿β2-MG含量，有减少碘对比剂急性肾损害的作用。
关键词：冠心胶囊；冠状动脉疾病；血清胱抑素C；尿β2-微球蛋白；介入治疗；对比剂；肾损害
中图分类号：R541.4 R289.5 文献标识码：B 文章编号：1672-1349(2011)07-0774-02
Influence of Guanxin Capsule on Cystain C and Urine β2-microglobulin in
Coronary Heart Disease after Percutaneous Coronary Intervention
Liang Hailong，Zhang Minzhou，Chen Qiuxing,et al
Guangdong Hospital of Traditional Chinese Medicine(Guangzhou 510120)
Abstract：Objective To investigate the effect ofGuanxin capsule on cystain C and urine β2-microglobulin(β2-MG) in patients with coronary heart disease after percutaneous coronary intervention(PCI).Methods Sixty-four patients were randomly divided into two groups:Control group(n32) treated with routine western medicine therapy，and treatment group(n32) treated withGuanxin capsule for 7 days.Results After treatment，the level of cystain C and urine β2-MG had no change compared with that beforeadministration in two groups(P>0.05).At 7 days，the level of cystain C and urine β2-MG in treatment group was significantly lower than that in control group(P<0.01).Conclusion Guanxin capsule had effect on contrast-induced acute kidney injury after PCI by reducing the level of cystain C and urine β2 -MG.
Key words：Guanxin capsule；coronary artery disease；cystain C；urine β2-microglobulin；percutaneous coronary intervention；contrast medium；kidney injury
经皮冠状动脉介入治疗(percutaneous coronary intervention ......
摘要：目的 观察冠心胶囊对冠心病介入术后患者肾功能指标血清胱抑素C(Cys C)及尿β2-微球蛋白(β2-MG)水平的影响。方法 将64例患者随机分为治疗组、对照组，各32例，两组疗程均为7 d，疗程结束后评定疗效。结果 治疗组与对照组比较，患者Cys C、尿β2-MG水平在治疗前、介入后48 h无统计学意义(P>0.05)；而在介入后7 d，Cys C水平治疗组为(0.86±0.14) g/L明显低于对照组(0.94±0.29) g/L(P<0.01)，尿β2-MG水平治疗组为(0.19±0.16) g/L明显低于对照组(0.33±0.27) g/L(P<0.01)。结论 冠心胶囊能明显降低Cys C、尿β2-MG含量，有减少碘对比剂急性肾损害的作用。
关键词：冠心胶囊；冠状动脉疾病；血清胱抑素C；尿β2-微球蛋白；介入治疗；对比剂；肾损害
中图分类号：R541.4 R289.5 文献标识码：B 文章编号：1672-1349(2011)07-0774-02
Influence of Guanxin Capsule on Cystain C and Urine β2-microglobulin in
Coronary Heart Disease after Percutaneous Coronary Intervention
Liang Hailong，Zhang Minzhou，Chen Qiuxing,et al
Guangdong Hospital of Traditional Chinese Medicine(Guangzhou 510120)
Abstract：Objective To investigate the effect ofGuanxin capsule on cystain C and urine β2-microglobulin(β2-MG) in patients with coronary heart disease after percutaneous coronary intervention(PCI).Methods Sixty-four patients were randomly divided into two groups:Control group(n32) treated with routine western medicine therapy，and treatment group(n32) treated withGuanxin capsule for 7 days.Results After treatment，the level of cystain C and urine β2-MG had no change compared with that beforeadministration in two groups(P>0.05).At 7 days，the level of cystain C and urine β2-MG in treatment group was significantly lower than that in control group(P<0.01).Conclusion Guanxin capsule had effect on contrast-induced acute kidney injury after PCI by reducing the level of cystain C and urine β2 -MG.
Key words：Guanxin capsule；coronary artery disease；cystain C；urine β2-microglobulin；percutaneous coronary intervention；contrast medium；kidney injury
经皮冠状动脉介入治疗(percutaneous coronary intervention ......
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