【摘 要】 目的:治疗D-炔诺孕酮埋植剂(Norplant)皮下埋植术后的副作用——月经紊乱。方法:接受Norplant避孕术后月经紊乱的292例患者按临床症状随机分两组，分别用尼尔雌醇、6-氨基己酸治疗。结果：尼尔雌醇组调经、止血效果明显优于6-氨基己酸组，且疗程短、复发率低。统计学处理两组有显著性差异(P<0.01)。结论：Norplant致月经紊乱与卵巢功能、雌孕激素水平有关。用尼尔雌醇治疗，可减轻不良反应，治疗月经紊乱，降低取出率和提高使用率。

    【关键词】 尼尔雌醇； D-炔诺孕酮； 6-氨基己酸； 月经紊乱

    Effect of nylestriol in treatment of norplant-induced menstrual disturbance

    WU Shuhui

    Nanshan District Family Planning Service Center, Guangdong Shenzhen 518052， China

    【Abstract】 Objectives: To observe the effect of nylestriol in the treatment of norplant-induced menstrual disturbance. Methods: Two hundred and ninety-two patients who suffered from menstrual disturbance after norplant contraception were randomly divided into the experiment group and the control group. Nylestriol was applied to the experiment group while 6-aminocaproic acid applied to the control. Results: The experiment group showed significantly better effects than the control group in menstruation normalization and hemostatis (P<0.01). In addition, nylestriol took shorter treatment course and revealed lower recurrence rate. Conclusion: Norplant-induced menstrual disturbance is related to ovarian function and estrogen, progesterone levels. Nylestriol can effectively reduce the side effects of norplant and treat menstrual disturbance. ......