【摘要】目的：对液基薄层细胞学检查与阴道镜活检在宫颈癌筛查中的应用价值进行评价研究分析。方法：选取我院2012年5月至2014年3月行宫颈癌筛查的妇科患者440例，采用随机数字表法分为两组，观察组220例采用液基薄层细胞学检查，对宫颈部分细胞进行基薄层细胞检测，检测结果用巴氏系统细胞学进行分类诊断。对照组220例行阴道镜活检。结果：观察组液基薄层细胞检测法诊断阳性167 例，阳性符合率为74.5%(164/220)； 对照组阴道镜活检法诊断阳性115例，阳性符合率为52.3%(115/220)，两组阳性符合率比较，有显著差异，具有统计学意义(P<0.05)。结论：将液基薄层细胞学检查技术应用宫颈细胞涂片筛查，细胞涂片宫颈异常细胞检出率得到明显提高。检出的巴氏系统报告方式内容易懂、直观、具体。

    【关键词】宫颈癌；液基薄层细胞检测； 阴道镜活检筛查；早期诊断

    【Abstract】Objectives： To compare the application value of liquid based thin-layer cell detection and colposcopy biopsy in cervical cancer screening. Methods： 440 patients with gynecological cervical cancer in hospital from May 2012 to March 2014 were selected and randomly divided into two groups. 220 patients in observation group received liquid based thin-layer cell detection. The cervical portion cell was detected through based liquid thin-layer cell detection. The detection results were classified by papanicolaou cytology diagnosis system. 220 patients were treated through colposcopy biopsy as control group. Results： 167 cases in the observation group received liquid based thin-layer cell detection were positive and the positive rate was 74.5% (164/220)； 115 cases in control group received colposcopy biopsy was positive and the positive rate was 52.3% (115/220). The difference in the positive rates between the two groups was statistically significant (P<0.05). Conclusion：The liquid based thin-layer cell detection in cervical smear screening has a high detection rate of cervical abnormal cell ......