重组人干扰素α—2b凝胶治疗慢性宫颈炎疗效观察(1)
【摘 要】目的：本文就重组人干扰素α-2b凝胶在慢性宫颈炎治疗中的应用效果进行研究。方法：选取我科在2017年2月--10月收治的92例慢性宫颈炎患者，依据来院顺序单双号将其分为两组，46例单号者设为参照组，治疗方法为微波治疗；将46例双号者设为实验组，在微波基础上加用重组人干扰素α-2b凝胶治疗，较比二组患者的治疗总有效率、康复时间及免疫指标。结果：实验组的治疗总有效率显著高于参照组(97.83%>84.78%)，阴道流血时间、阴道排液时间均短于参照组，实验组治疗后的IgA、IgM、IgG各免疫指标均优于参照组；组间比较P<0.05。结论：应用重组人干扰素α-2b凝胶治疗慢性宫颈炎可可获得显著效果，对促进宫颈创面愈合、增强机体抗病能力具有积极作用，值得推广。
【关键词】重组人干扰素α-2b；凝胶；慢性宫颈炎
Abstract Objective： To study the effect of recombinant human interferon alpha -2b gel in the treatment of chronic cervicitis. Methods： 92 patients with chronic cervicitis treated in our department in --10 month of February 2017 were divided into two groups according to the order single and double number of the hospital. 46 cases of single number were set up as the reference group and the treatment method was microwave treatment. 46 cases of double numbers were set up as experimental group， combined with recombinant human interferon alpha -2b gel on the basis of microwave， compared with two groups. The total effective rate， recovery time and immune index of the patients were analyzed. Results： the total effective rate of treatment in the experimental group was significantly higher than that of the reference group (97.83%>84.78%). The time of vaginal bleeding and the time of vaginal discharge were shorter than those of the reference group. All the immune indexes of IgA， IgM and IgG in the experimental group were superior to those of the reference group； the group was compared with the group P<0.05. Conclusion： the application of recombinant human interferon alpha -2b gel in the treatment of chronic cervicitis cacao has a significant effect. It has a positive effect on promoting the healing of cervical wound and enhancing the body resistance to disease. It is worth popularizing.
Key words： recombinant human interferon alpha -2b； gel； chronic cervicitis
【中图分类号】R711.32 【文献标识码】A 【文章编号】1672-3783(2018)07-03--01
慢性宫颈炎是临床中常见的妇科疾病，好发于经产妇女中，主要是由細菌、病毒感染所引发[1]。患者在发病后，会出现子宫颈肥大、子宫颈腺体囊肿、子宫颈管炎、子宫颈鳞状上皮生化等表现；宫颈分泌也会有明显变化，是以白带增多、黏稠状脓性白带为主要症状，颜色呈乳白色或微黄色，部分患者还会出现血性或夹杂血丝白带；该病不仅危害患者的生殖系统健康，还会对其生活质量造成一定影响。为使患者获得更为理想的治疗效果，我科对部分患者采用重组人干扰素α-2b凝胶，效果较令人满意。
1 基线资料及方法
1.1 基线资料数据
选取2017年2月--10月在我科接受治疗的慢性宫颈炎患者作为此次研究对象，样本数量为92例，入院后行阴道镜检查及阴道分泌物检查等，符合《妇产科学》(第8版)中关于慢性宫颈炎的诊断标准[2]。依据来院顺序单双号将其分为两组，46例单号者设为参照组，46例双号者设为实验组。实验组患者的年龄分布在23--48岁范围内，中位年龄为(38.2±4.5)岁；孕次为1--3次；病程在0.5--5.5年之间不等。参照组患者的年龄分布在24--46岁范围内，中位年龄为(38.7±4.2)岁；孕次为1--3次；病程在0.5--6年之间不等。对比两组数据，P>0.05无统计学意义。
排除标准：将肝肾功能不全者、伴有严重心脑血管疾病者、处于妊娠期或哺乳期者、两个月内使用过避孕药者、恶性肿瘤者予以排除。所有患者对于本次研究均有知情权，并自愿参与研究。, http://www.100md.com(胡美菊)
【关键词】重组人干扰素α-2b；凝胶；慢性宫颈炎
Abstract Objective： To study the effect of recombinant human interferon alpha -2b gel in the treatment of chronic cervicitis. Methods： 92 patients with chronic cervicitis treated in our department in --10 month of February 2017 were divided into two groups according to the order single and double number of the hospital. 46 cases of single number were set up as the reference group and the treatment method was microwave treatment. 46 cases of double numbers were set up as experimental group， combined with recombinant human interferon alpha -2b gel on the basis of microwave， compared with two groups. The total effective rate， recovery time and immune index of the patients were analyzed. Results： the total effective rate of treatment in the experimental group was significantly higher than that of the reference group (97.83%>84.78%). The time of vaginal bleeding and the time of vaginal discharge were shorter than those of the reference group. All the immune indexes of IgA， IgM and IgG in the experimental group were superior to those of the reference group； the group was compared with the group P<0.05. Conclusion： the application of recombinant human interferon alpha -2b gel in the treatment of chronic cervicitis cacao has a significant effect. It has a positive effect on promoting the healing of cervical wound and enhancing the body resistance to disease. It is worth popularizing.
Key words： recombinant human interferon alpha -2b； gel； chronic cervicitis
【中图分类号】R711.32 【文献标识码】A 【文章编号】1672-3783(2018)07-03--01
慢性宫颈炎是临床中常见的妇科疾病，好发于经产妇女中，主要是由細菌、病毒感染所引发[1]。患者在发病后，会出现子宫颈肥大、子宫颈腺体囊肿、子宫颈管炎、子宫颈鳞状上皮生化等表现；宫颈分泌也会有明显变化，是以白带增多、黏稠状脓性白带为主要症状，颜色呈乳白色或微黄色，部分患者还会出现血性或夹杂血丝白带；该病不仅危害患者的生殖系统健康，还会对其生活质量造成一定影响。为使患者获得更为理想的治疗效果，我科对部分患者采用重组人干扰素α-2b凝胶，效果较令人满意。
1 基线资料及方法
1.1 基线资料数据
选取2017年2月--10月在我科接受治疗的慢性宫颈炎患者作为此次研究对象，样本数量为92例，入院后行阴道镜检查及阴道分泌物检查等，符合《妇产科学》(第8版)中关于慢性宫颈炎的诊断标准[2]。依据来院顺序单双号将其分为两组，46例单号者设为参照组，46例双号者设为实验组。实验组患者的年龄分布在23--48岁范围内，中位年龄为(38.2±4.5)岁；孕次为1--3次；病程在0.5--5.5年之间不等。参照组患者的年龄分布在24--46岁范围内，中位年龄为(38.7±4.2)岁；孕次为1--3次；病程在0.5--6年之间不等。对比两组数据，P>0.05无统计学意义。
排除标准：将肝肾功能不全者、伴有严重心脑血管疾病者、处于妊娠期或哺乳期者、两个月内使用过避孕药者、恶性肿瘤者予以排除。所有患者对于本次研究均有知情权，并自愿参与研究。, http://www.100md.com(胡美菊)