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急性脑梗死患者血清HCY水平的变化与脂质过氧化关系的探讨
http://www.100md.com 2011年3月1日 朱延荣
同型半胱氨酸,丙二醛,超氧化物歧化酶,谷胱甘肽过氧化物酶
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     [摘要]目的:探讨了急性脑梗死患者血清HCY水平的变化与脂质过氧化的关系。方法:应用酶联法和化学比色法对36例急性脑梗死患者进行了血清HCY水平和脂质过氧化水平检测,并与35名正常健康人作比较。结果:急性脑梗死患者血清HCY、MDA水平非常显著地高于正常人组(P<0.01),而SOD、GSH-PX水平则非常显著地低于正常人组(P<0.01),血清HCY水平与MDA水平呈正相关(r=0.6018,P<0.01),与SOD、GSH-PX水平呈显著负相关(r=-0.4782,-0.5014,P<0.01)。结论:急性脑梗死患者的发生发展与HCY和脂质过氧化的关系密切相关。

    [关键词]急性脑梗死;同型半胱氨酸;丙二醛;超氧化物歧化酶;谷胱甘肽过氧化物酶

    [Abstract]ObjectiveTo study the relationship between changes of serum HCY and Lipid peroxidation levels in patients with acute cerebral infarction .MethodsSerum HCY (with Elisa).Serum SOD、MDA、GSH-PX(with Colorimetry)levels were measured in 36 patients with acute cerebral infarction and 35 controls. ResultsLevels of serum HCY、MDA were significantly higher in the patients than those in controls(P<0.01 ),but serum SOD、GSH-PX levels were significantly lower in the patients than those in controls(P<0 ......

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