骨形成蛋白-2促人肺癌A549细胞株基质金属蛋白酶合成分泌的机制研究(5)
[15] Donnini S，Morbidelli L，Taraboletti G，et al. ERK1-2 and p38 MAPK regulate MMP/TIMP balance and function in response to thrombospondin-1 fragments in the microvascular endothelium. Life Sci，2004，74(24)：2975-2985
[16] Holvoet S，Vincent C，Schmitt D，Serres M. The inhibition of MAPK pathway is correlated with down-regulation of MMP-9 secretion induced by TNF-alpha in human keratinocytes. Exp Cell Res，2003，290(1)：108-119
[17] Underwood DC，Osborn RR，Bochnowicz S，et al. SB 239063，a p38 MAPK inhibitor，reduces neutrophilia，inflammatory cytokines，MMP-9，and fibrosis in lung. Am J Physiol Lung Cell Mol Physiol，2000，279(5)：L895-902
[18] Esteve PO，Robledo O，Potworowski EF，et al. Induced expression of MMP-9 in C6 glioma cells is inhibited by PDGF via a PI 3-kinase-dependent pathway. Biochem Biophys Res Commun，2002，296(4)：864-869
[19] Zahradka P，Harding G，Litchie B，et al. Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP. Am J Physiol Heart Circ Physiol，2004，287(6)：H2861-H2870
[20] Zhang D，Bar-Eli M，Meloche S，et al.Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor：the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals. J Biol Chem，2004，279(19)：19683-19690
[21] Vinals F，Lopez-Rovira T，Rosa JL，et al. Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2. FEBS Lett，2002，510(1-2)：99-104, 百拇医药(唐四元 谢 辉 罗自强)
[16] Holvoet S，Vincent C，Schmitt D，Serres M. The inhibition of MAPK pathway is correlated with down-regulation of MMP-9 secretion induced by TNF-alpha in human keratinocytes. Exp Cell Res，2003，290(1)：108-119
[17] Underwood DC，Osborn RR，Bochnowicz S，et al. SB 239063，a p38 MAPK inhibitor，reduces neutrophilia，inflammatory cytokines，MMP-9，and fibrosis in lung. Am J Physiol Lung Cell Mol Physiol，2000，279(5)：L895-902
[18] Esteve PO，Robledo O，Potworowski EF，et al. Induced expression of MMP-9 in C6 glioma cells is inhibited by PDGF via a PI 3-kinase-dependent pathway. Biochem Biophys Res Commun，2002，296(4)：864-869
[19] Zahradka P，Harding G，Litchie B，et al. Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP. Am J Physiol Heart Circ Physiol，2004，287(6)：H2861-H2870
[20] Zhang D，Bar-Eli M，Meloche S，et al.Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor：the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals. J Biol Chem，2004，279(19)：19683-19690
[21] Vinals F，Lopez-Rovira T，Rosa JL，et al. Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2. FEBS Lett，2002，510(1-2)：99-104, 百拇医药(唐四元 谢 辉 罗自强)