凌征梅(广东省梅州市中医医院 梅州 514000)

    Abstract：Objective：To probe into the effectiveness and safety of fluoxetine combined with olanzapine in the treatment of depression. Methods：90 patients with depression and who accepted treatments in our hospital from June，2014 to June，2015 were selected，and were divided into the observation group of 45 cases and the control group of 45 cases by the two color random grouping method.In the control group，they were treated with fluoxetine while in the observation group，they were treated with the fluoxetine combined with olanzapine.Then，the clinical treatment effects of two groups of patients were observed Outcome：The total effective rate in the observation group was 75.55%，which was higher than that in the control group of 46.67%；And the incidence rate of adverse reactions in the observation group was 20%，which lower than that in the control group of 37.78%(P<0.05)；There was no significant difference in the HAMD score between the two groups before treatment.After treatment，the HAMD score of the patients in the observation group was significantly lower than that in the control group(P<0.05).Conclusion：For the patients with depression ......