诺和灵30R和甘精胰岛素对2型糖尿病的疗效观察(2)
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综上所述，根据该研究结果可知诺和灵30R和甘精胰岛素均可安全有效地降低血糖，但使用诺和灵30R容易引起低血糖，提示在使用时应加强血糖的监测。二者对病人体重影响小，具有安全、方便的特点，是2型糖尿病理想的治疗方案。
[参考文献]
[1]UK Prospective Diabetes Study(UKPDS)Group. Intensive blood glucose control with sulphonylureas or insulin compared with convetional treatment and risk of complications in patients with type 2 diabetes(UKPDS 33)[J].Lancet，1998，352:837-853.
[2]Wright A， Burden AC，Paisey RB，et al.Sulfonylurea inadequacy: efficacy of addition of insulin over 6 years in patients with type 2 diabetes in the UK.Prospective Diabetes Study(UKPDS 57)[J].Diabetes Care，2002，25:330-336.
[3]Cryer PE. Hypoglycemia is the limiting factor in the management of diabetes[J].Diabete Metab Res Rev，1999，15(1): 42-46.
[4]Bolli GB，Owen DR.Insulin glargine[J].Lancet，2000，56(9228):443-445.
[5]Rosenstock J，Schwartz SL，Clark C，et al.Basal insulin therapy in type 2 diabetes:27-week comparison of insulin glargine(HOM901) and NPH insulin[J].Diabetes Care，2001，24 (11):631-636.
[6]Riddle MC，Rosenstock J，Gerich J.The treat-to-target trial randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetes patients[J].Diabetes Care，2003，26 (11):3080-3086.
[7]Rossetti P，Pampanelli S，Fanclli C，et al.Intensive replacement of basal insulin in patients with type 1 diabetes given rapid-acting insulin analog at meal time: a 3-month comparison between administration of NPH insulin four times daily and glargine insulin at dinner or bed time[J].Diabetes Care，2003，26(5):1490-1496.
(收稿日期:2008-03-12)
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