茉莉花提取液对老龄小鼠的抗氧化作用
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[摘要] 目的：探讨茉莉花提取液对老龄小鼠的抗氧化作用。方法：将老龄小鼠随机分为老龄茉莉花提取液组和老龄生理盐水组，每组8只，另设8只青年小鼠作为青年生理盐水组，三组连续灌胃28 d，1次/d，第29天处死小鼠，迅速取其心、脑组织测定超氧化物歧化酶(SOD)、丙二醛(MDA)的含量。结果：老龄茉莉花提取液组比老龄生理盐水组SOD的含量有显著升高(P<0.01)，比青年生理盐水组低(P<0.01)；老龄茉莉花提取液组比老龄生理盐水组MDA的含量有显著的降低(P<0.01)，与青年生理盐水组无明显差异(P>0.05)。结论：茉莉花提取液对老龄小鼠机体能起到显著的抗氧化作用，具有一定的抗衰老作用。
[关键词] 茉莉花；自由基；超氧化物歧化酶(SOD)；丙二醛(MDA)
[中图分类号] R329.3[文献标识码]A [文章编号]1673-7210(2009)02(b)-017-02
The antioxidant effect of jasmine extracts to the old mice
DENG Yan1, QIN Li-jia1, TAN Jun1, XU Fang-yan1, ZHAO Shan-min2△, HE Xian-jiao2, JIN Ling2
(1.2005 Undergraduate Course of Clinical Medicine, Youjiang Medical College for Nationalities, Baise533000,China;2.Physiology Department, Youjiang Medical College for Nationalities,Baise533000, China)
[Abstract] Objective: To explore the antioxidant effect of jasmine extracts to the old mice. Methods: The old mice were randomly divided into two groups, the old-age jasmine-extracts group and the old-age NS group, each group had eight porcines, and took the eight youth mice as the youth NS group.Three groups animals had been poured into stomach with jasmine-extracts and NS for 28 days respectively, one time a day. On the 29th day,the mice were sacrificed and took its heart and brain away. To detect the content of SOD and MDA. Results: In the heart and brain tissues, the content of SOD in the old-age jasmine-extracts groups was significantly increased as compared with the old-age NS group(P<0.01),but it was lower than the youth NS group(P<0.01);the content of MDA in the old-age jasmine-extracts groups was decreased significantly as compared with the old-age NS group(P<0.01),but it had no significant difference with the youth NS group(P>0.05). Conclusion: The jasmine extracts can play the remarkable antioxidant effect and has certain anti-aging effect in the old age mouse.
[Key words] Jasmine; Free radical; Superoxide dismutase(SOD); Malondialdehyde (MDA)
随着社会逐渐步入老龄化阶段，衰老及老年群体的健康问题已成为了医学领域的热门研究。大量研究证实茉莉花中含有黄酮等多种生物活性物质[1，2]，对机体具有一定的抗氧化、降血压等作用[2-4] ......
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