老年心绞痛患者血清脂联素、抵抗素与C-反应蛋白的变化分析(1)
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[摘要] 目的:探讨不稳定型心绞痛(UAP)患者血清脂联素、抵抗素与C-反应蛋白(CRP)水平在治疗前后的变化及在动脉粥样硬化发展中的病理生理意义。方法:选取25例UAP(UAP组)患者和20例正常人(对照组),分别检测UAP组治疗前后及对照组血清脂联素、抵抗素、CRP水平,并进行比较。结果:UAP组治疗前血清抵抗素、CRP水平高于对照组(P<0.05),脂联素水平低于对照组(P<0.05),血清脂联素水平与抵抗素、CRP水平呈负相关,抵抗素水平与CRP水平呈正相关。UAP组治疗后抵抗素和CRP水平下降,脂联素水平升高(P<0.05)。结论:脂联素和抵抗素是冠状动脉疾病的独立危险因素,将冠心病与内分泌密切联系在一起。CRP是敏感的炎症指标,具有促炎效应,参与AS的致病过程。三者可能共同促进了AS的发展。
[关键词] 动脉粥样硬化;脂联素;抵抗素;CRP
[中图分类号] R714.252[文献标识码]A [文章编号]1673-7210(2009)08(b)-018-04
The analysis of serum level change of adiponetin, resistin and CRP in old patients with UAP
SANG Li, ZHUANG Jun
(Department of Comprehensive 1, Dalian Central Hospital, Dalian 116033, China)
[Abstract] Objective: To evaluate the changes ofthe serum level of adiponetin, resistin and CRP in old patients with unstable angina pectoris (UAP) before and after the therapy and their possible significant in the devolopment of AS ......
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