抑癌基因FHIT和PTEN在肝细胞癌中的表达及其意义(4)
 |
| 第1页 |
参见附件(4322KB，5页)。
[4]Ohta M, Inoue H, Cotticelli MG, et al. The FHIT gene, spanning the hromosome 3p14.2 fragile site and renal carcinoma -associated t(3;8) breakpoint, is abnormal in digestive tract cancers [J]. Cell,1996,84(4):587-597.
[5]Pace HC, Garrison PN, Robinson AK, et al. Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit [J]. Proc Natl Acad Sci USA,1998,95(10):5484-5489.
[6]Huebner K, Croce CM. Cancer and the FRA3B/FHIT fragile locus: it's a HIT [J]. Br J Cancer,2003,88(10):1501-1506.
[7]Zhao P, Song X, Nin YY, et al. Loss of fragile histidine triad protein in human hepatocellular carcinoma [J]. World J Gastroenterol,2003,9(6):1216-1219.
[8]赵坡,宋欣,宁元元,等.肝细胞癌脆性组氨酸三联体Fhit蛋白表达丢失研究[J].中华肝胆外科杂志,2004,10(1):52-54.
[9]Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast and prostate cancer [J]. Science,1997,275(2):1943-1947.
[10]Whang YE, Wu X, Suzuki H, et al. Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression [J]. Proc Natl Acad Sci USA,1998,95(6):5246-5250.
[11]周旭,易继林,郭悦青,等.PTEN与hTERT在肝细胞肝癌中的表达及其相关性研究[J].中华实验外科杂志,2005,22(1):55-57.
[12]Frank BF, Huan SH J, Webster K. The bhosbhoinositol bhosphatase activity of PTEN mediates a serum sensitive G1 growth arrest in glioma cells [J]. Cancer Res,1998,58(18):5002-5006.
(收稿日期:2010-02-02)
您现在查看是摘要介绍页，详见PDF附件(4322KB，5页)。