剖宫产术后连续硬膜外自控镇痛对产妇及血清泌乳素水平的影响
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[摘要] 目的：探讨剖宫产术后连续硬膜外自控镇痛对产妇及血清泌乳素水平的影响。方法：选取2008年1月~2009年1月进行剖宫产的800例产妇为研究对象，将其随机分为观察组(连续硬膜外自控镇痛组)400例和对照组(杜非合剂镇痛组)400例，将两组产妇的术后不同时段VAS评分、QOL评分及血清泌乳素、CRP、IL-8及IL-6水平进行统计及比较。结果：观察组的术后6 h、12 h及24 h的VAS评分低于对照组，QOL评分高于对照组，血清泌乳素高于对照组，血清CRP、IL-8及IL-6水平低于对照组，差异均有统计学意义(P<0.05)。结论：剖宫产术后连续硬膜外自控镇痛对产妇机体及血清泌乳素水平影响较小，值得临床推广应用。
[关键词] 剖宫产；连续硬膜外自控镇痛；产妇；血清泌乳素；影响
[中图分类号] R719.8 [文献标识码]A[文章编号]1673-7210(2011)03(b)-029-02
The study on the influence of PCEA after caesarean section for the maternal and serum prolactin
CHEN Xiaoli1, SHEN Yawei2
1. The Fifth Hospital of Zhangjiakou City, Hebei Province, Zhangjiakou 075000, China; 2. MCH Hospital of Zhangjiakou City, Hebei Province, Zhangjiakou 075000, China
[Abstract] Objective: To study the influence of PCEA after caesarean section for the maternal and serum Prolactin. Methods: 800 maternal in our hospital from January 2008 to January 2009 were selected as research object, then they were randomly divided into observation group(PCEA group)400 cases and control group (dolantin and promethazine group) 400 cases, then VAS score, QOL score and serum PRL, CRP, IL-8 and IL-6 of two groups after delivery at different time were analyzed and compared. Results: The VAS score after delivery at 6,12 and 24 hours were all lower than those of control group, QOL score were all higher than those of control group, serum PRL were higher than those of control group, serum CRP, IL-8 and IL-6 were lower than those of control group, there were all significant differences(P<0.05). Conclusion: The influence of PCEA after caesarean section for the maternal and serum Prolactin is smaller, and it is worthy of application and dissemination.
[Key words] Caesarean section; PCEA; Maternal; Serum prolactin; Influence
产后镇痛是减轻产妇产后疼痛，提高其生存质量的方法，近年来在临床上的应用越来越广泛，在剖宫产中对患者的各项影响仍存在争议，尤其是对血清、免疫等多方面的影响[1]。本文中笔者就剖宫产术后连续硬膜外自控镇痛对产妇及血清泌乳素水平的影响进行研究，现将结果总结报道如下：
1 资料与方法
1.1 一般资料
选取2008年1月~2009年1月于我院和张家口妇幼保健院进行剖宫产的800例产妇作为研究对象，将其随机分为观察组(连续硬膜外自控镇痛组)400例和对照组(杜非合剂镇痛组)400例。对照组的400例产妇中，年龄21~38岁，平均(26.5±4.2)岁；孕周37+2~40+5周；文化程度：大专及以上156例 ......
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