倍他乐克联合硝苯地平缓释片治疗原发性高血压疗效观察(1)
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[摘要] 目的：探讨倍他乐克联合硝苯地平缓释片治疗原发性高血压的临床疗效。方法：将我院新近发现的60例原发性高血压患者，随机分为对照组和治疗组，每组各30例。对照组给予硝苯地平缓释片10 mg/次，每日2次于早8点和晚8点口服；治疗组硝苯地平缓释片用法同对照组，但于午餐前增加口服倍他乐克25 mg。每周测血压2次，共8周。结果：对照组显效11例，有效11例，无效8例，总有效率为73.3%(22/30)；治疗组显效18例，有效11例，无效1例，总有效率为96.7%(29/30)。两组总有效率比较，差异有统计学意义(χ2=7.134，P<0.05)。对照组治疗前后心率无明显改变(P>0.05)；治疗组心率平均下降10次/min，与治疗前及对照组相比差异均有统计学意义(均P<0.05)。结论：倍他乐克联合硝苯地平缓释片治疗原发性高血压疗效好，且有相互协同作用，值得临床推广。
[关键词] 倍他乐克；硝苯地平缓释片；原发性高血压
[中图分类号] R544.1 [文献标识码] A [文章编号] 1673-7210(2011)07(a)-018-03
Clinical effect observation on Nifedipine Sustained-release Tablet combined with Betaloc in the treatment of essential hypertension
DING Shaoxiang
Department of Cardiology, Kangle Hospital of Qinghai Province, Xining 810006, China
[Abstract] Objective: To investigate the clinical efficacy of Nifedipine Sustained-release Tablets combined with Betaloc in the treatment of essential hypertension. Methods: 60 cases of essential hypertension were discovered recently and divided into treatment group and control group in random, 30 patients in each group. The control group were given Nifedipine Sustained-release Tablets with 10 mg, twice a day at 8 am and 8 pm oral; treatment group were given the same of Nifedipine Sustained-release Tablets with control group, but increased Betaloc 25 mg before lunch. blood pressure of two groups were measured twice a week and total of 8 weeks. Results: In control group, significant therapeutic effect in 11 cases, there were clear therapeutic effect in 11 cases, no treatment effect in 8 cases, the total therapeutic efficacy was 73.3% (22/30); in treatment group, significant therapeutic effect in 18 cases, there were clear therapeutic effect in 11 cases, no treatment effect in 1 case, the total therapeutic efficacy was 96.7% (29/30); there was a significant difference between two groups (χ2=7.134， P<0.05). In control group, there was no significant change in heart rate before adn after the treatmont (P>0 ......
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