血栓通治疗冠心病心绞痛的临床观察(1)
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[摘要] 目的：研究血栓通注射液治疗冠心病心绞痛的临床效果。方法：将100例冠心病心绞痛患者随机分为治疗组(50例)和对照组(50例)。两组常规给予西药抗心绞痛治疗，治疗组加用血栓通注射液。观察两组患者的心绞痛缓解，心电图心肌缺血改善情况，血脂、血液流变学各指标的变化。结果：治疗组心绞痛缓解总有效率(98%)明显高于对照组(80%)(P<0.01)，两组治疗后心电图示心肌缺血改善情况、血脂、血液流变学各指标比较，差异均有统计学意义(P<0.01或P<0.05)。结论：血栓通注射液治疗冠心病心绞痛疗效显著，安全可靠，具有较高的临床应用价值。
[关键词] 冠心病；心绞痛；血栓通注射液
[中图分类号] R541.4 [文献标识码]A[文章编号]1673-7210(2011)07(c)-014-03
Clinical effect on Xueshuantong Injection in the treatment of coronary heart disease and angina
CAO Hui, LU Changhong, NIE Guanglin
The People′s Hospital of Yuechi County, Sichuan Province, Yuechi 638300, China
[Abstract] Objective: To study the clinical effect on Xueshuantong Injection in the treatment of coronary heart disease and angina. Methods: 100 patients with angina of coronary heart disease were randomly divided into treatment group (50 cases) and control group (50 cases). Patients in treatment group were treated with routine regimen and Xueshuantong Injection; patients in control group were treated with routine regimen. Indicators of the clinical manifestation of angina, myocardial ischemia judged by electrocardiogram, blood lipids and blood rheology in two groups were observed. Results: The total effective rate of improvement of clinical manifestation of angina were 98.00% and 80.00% in treatment group and control group respectively (P<0.01); there were significant differences of improvement of myocardial ischemia judged by electrocardiogram, blood lipids and blood rheology between two groups after treatment (P<0.01 or P<0.05). Conclusion: Xueshuantong Injection has markedly effect with little side one on angina of coronary heart disease, it is worthy to use in application.
[Key words] Angina; Coronary heart disease; Xueshuantong Injection
冠心病心绞痛是由于冠状动脉粥样硬化、狭窄或痉挛，导致心肌发生急剧而短暂的缺血、缺氧引起的一种临床综合征。临床单用硝酸酯类药物治疗冠心病心绞痛，对13%的患者无效，因硝酸酯类药物只有扩张冠状血管的作用，而无抗血栓和抗凝血作用[1]。临床报道血栓通注射液治疗冠心病心绞痛疗效显著[1-4]。为了进一步探讨血栓通注射液在治疗冠心病心绞痛中的疗效及应用价值，选择经中西医确诊的冠心病心绞痛患者50例，在常规抗心绞痛治疗基础上给予血栓通注射液治疗，并经临床对照观察，取得了较好的效果。现报道如下：
1 资料与方法
1.1 一般资料
选取我院冠心病心绞痛患者100例，随机将其分为治疗组(50例)和对照组(50例)。两组患者性别、年龄、病程及心绞痛发作情况比较差异无统计学意义(P>0.05)，具有可比性。见表1。
1.2 诊断标准
1.2.1 西医诊断标准冠心病心绞痛诊断参照ACC/AHA 2002年最新发布的《ST段抬高心肌梗死治疗指南》[5] ......
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